Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Composition of Balance Sheet Items - Property and Equipment (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Property and equipment
Property and equipment, gross	$ 29,696		$ 33,409
Less accumulated depreciation and amortization	(12,481)		(16,454)
Property and equipment, net	17,215		16,955
Depreciation and amortization expense	700	$ 600
Lab equipment and furniture
Property and equipment
Property and equipment, gross	12,199		12,287
Leasehold improvements
Property and equipment
Property and equipment, gross	13,998		14,369
Software
Property and equipment
Property and equipment, gross	2,185		4,776
Computer equipment
Property and equipment
Property and equipment, gross	1,282		1,944
Construction in Progress
Property and equipment
Property and equipment, gross	$ 32		$ 33