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Share-Based Payments (Tables)
3 Months Ended
Mar. 31, 2022
Share-based Payment Arrangement [Abstract]  
Schedule of share-based compensation expense Share-based compensation expense is as follows (dollars in thousands):
Three Months ended
March 31,
20222021
(unaudited)
Research and development$651 $588 
Selling, general and administrative3,374 3,783 
Total$4,025 $4,371 
Summary of stock options and SAR activities The following table summarizes stock option and stock appreciation rights (SAR) activities:
Number of
Options
Weighted
Average
Exercise Price
Weighted
Average
Remaining
Contractual
Term (in years)
Outstanding, December 31, 20215,774,076 $24.15 5.95
Granted 929,785 $32.20 
Exercised (47,601)$18.21 
Forfeited (48,036)$30.84 
Outstanding, March 31, 2022 (unaudited)6,608,224 $25.28 6.25
As of December 31, 2021:
Vested and expected to vest5,774,076 $24.15 5.95
Exercisable3,651,824 $21.29 4.53
As of March 31, 2022:
Vested and expected to vest6,608,224 $25.28 6.25
Exercisable 4,280,012 $22.87 4.79
Summary of restricted stock units
The following table summarizes restricted stock unit (RSU) activities:
Number of
RSUs
Weighted Average
Grant Date Fair Value per Share
Nonvested, December 31, 202121,110 $29.61 
Granted131,210 $32.20 
Vested(21,110)$29.61 
Forfeited— $— 
Nonvested, March 31, 2022131,210 $32.20 
Summary of performance stock unit
The following table summarizes performance share unit (PSU) activities:
Performance-Based UnitsMarket-Based UnitsTotal PSUs
Number of PSUsWeighted
Average
Grant Date Fair Value per Share
Number of PSUsWeighted
Average
Grant Date Fair Value per Share
Number of PSUsWeighted
Average
Grant Date Fair Value per Share
Nonvested, December 31, 202153,500 $29.82 35,625 $26.34 89,125 $28.43 
Vested(21,500)$29.67 — (21,500)$29.67 
Nonvested, March 31, 202232,000$29.92 35,625$26.34 67,625$28.04