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Investments - Narrative (Details) - USD ($)
1 Months Ended 12 Months Ended
Apr. 30, 2020
Dec. 31, 2021
Dec. 31, 2020
Variable Interest Entity [Line Items]      
Impairment due to credit losses   $ 0 $ 0
Cash received from sale of subsidiary   12,900,000  
Navitor Pharmaceuticals, Inc.      
Variable Interest Entity [Line Items]      
Agreement termination notice period 30 days    
Threshold for development costs payments $ 50,000,000    
Payment for option issue fee $ 10,000,000    
Navitor Pharmaceuticals, Inc. | Variable Interest Entity, Not Primary Beneficiary      
Variable Interest Entity [Line Items]      
Investments   $ 15,000,000  
VIE, qualitative or quantitative information, ownership percentage 13.00%