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Income Taxes - Narrative (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Jun. 09, 2020
Dec. 31, 2018
Operating Loss Carryforwards [Line Items]          
Valuation allowance related to acquisition $ 70,529 $ 582 $ 11 $ 70,500 $ 9
Research and development credit carryforwards 1,600        
Net tax benefit as a result of statutes of limitation 100 600 3,000    
Tax expense on uncertain tax positions 300 $ 300 $ 200    
Tax expense related to prior year position 200        
Adamas Pharmaceuticals          
Operating Loss Carryforwards [Line Items]          
Valuation allowance related to acquisition 69,700        
U.S. Federal          
Operating Loss Carryforwards [Line Items]          
NOL carryforwards 449,300        
NOLs utilized 7,200        
U.S. Federal | Adamas Pharmaceuticals          
Operating Loss Carryforwards [Line Items]          
NOL carryforwards 413,700        
State          
Operating Loss Carryforwards [Line Items]          
NOL carryforwards 431,900        
NOLs utilized 5,300        
State | Adamas Pharmaceuticals          
Operating Loss Carryforwards [Line Items]          
NOL carryforwards $ 387,300