Accounts Payable and Accrued Liabilities (Tables)

12 Months Ended

Dec. 31, 2021

Payables and Accruals [Abstract]

Schedule of accrued expenses and accrued liabilities

Accounts payable and accrued liabilities consist of the following (dollars in thousands):

	December 31, 2021		December 31, 2020
Accrued compensation	$	28,068	$	16,008
Accrued royalties (1)	13,821		13,890
Accrued clinical trial costs (2)	9,125		12,842
Accrued product costs	18,460		9,587
Accrued professional fees	26,728		7,730
Accounts payable	9,331		6,147
Operating lease liabilities, current portion (3)	6,477		3,760
Other accrued expenses	5,673		8,970
Total	$	117,683	$	78,934

(1) Refer to Note 15, Commitments and Contingencies.

(2) Includes preclinical and all clinical trial-related costs.

(3) Refer to Note 12, Leases.