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Share-Based Payments (Tables)
9 Months Ended
Sep. 30, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of share-based compensation expense Share-based compensation expense is as follows (dollars in thousands):
Three Months ended
September 30,
Nine Months ended
September 30,
2021202020212020
(unaudited)(unaudited)
Research and development$615 $777 $1,909 $2,276 
Selling, general and administrative3,412 3,713 11,965 11,164 
Total$4,027 $4,490 $13,874 $13,440 
Summary of stock options and SAR activities The following table summarizes stock option and stock appreciation rights (SAR) activities (unaudited):
Number of
Options
Weighted-
Average
Exercise Price
(per share)
Weighted-
Average
Remaining
Contractual
Term (in years)
Outstanding, December 31, 20205,451,862 $23.26 6.28
Granted 991,325 $28.93 
Exercised (233,347)$18.82 
Forfeited (410,488)$27.43 
Outstanding, September 30, 2021 (unaudited)5,799,352 $24.11 6.18
As of September 30, 2021:
Vested and expected to vest5,799,352 $24.11 6.18
Exercisable 3,679,177 $21.23 4.80
As of December 31, 2020:
Vested and expected to vest5,451,862 $23.26 6.28
Exercisable3,218,771 $19.36 4.77
Summary of restricted stock units
The following table summarizes restricted stock unit (RSU) activities (unaudited):
Number of
RSUs
Weighted-Average
Grant Date Fair Value per Share
Nonvested, December 31, 202026,055 $23.99 
Granted21,110 $29.61 
Vested(26,055)$23.99 
Forfeited— $— 
Nonvested, September 30, 202121,110 $29.61 
Summary of performance stock unit
The following table summarizes performance share unit (PSU) activities (unaudited):

Performance-Based UnitsMarket-Based UnitsTotal PSUs
Number of PSUsWeighted-
Average
Grant Date Fair Value per Share
Number of PSUsWeighted-
Average
Grant Date Fair Value per Share
Number of PSUsWeighted-
Average
Grant Date Fair Value per Share
Nonvested, December 31, 2020— $— 15,625 $23.41 15,625 $23.41 
Granted95,000 29.74 20,000 28.63 115,000 $29.55 
Vested(40,000)29.61(40,000)$29.61 
Forfeited(1,500)30.45(1,500)$30.45 
Nonvested, September 30, 202153,500$29.82 35,625$26.34 89,125$28.43