Commitments and Contingencies (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Additional period for which the entity may elect to extend the term of the lease			5 years
Additional tenant improvement allowance			$ 2,100,000
Tenant improvement allowance utilized	$ 49,000	$ 0	79,000	$ 0
Amount available for tenant improvements			400,000
Rent expense	500,000	$ 700,000	1,200,000	$ 1,300,000
Future minimum lease payments under non-cancelable operating leases
2017 (remaining)	1,468,000		1,468,000
2018	1,487,000		1,487,000
2019	1,344,000		1,344,000
Thereafter	454,000		454,000
Total	4,753,000		4,753,000
Rune HealthCare Limited
Future minimum lease payments under non-cancelable operating leases
Milestone payments due	$ 0		$ 0