Accrued Expenses (Details) - USD ($) $ in Thousands	Sep. 30, 2015	Dec. 31, 2014
Accrued Expenses
Accrued compensation	$ 7,711	$ 5,829
Accrued professional fees	7,309	2,049
Accrued clinical trial and clinical supply costs	1,693	2,942
Accrued sales and marketing expenses	1,007	1,017
Accrued product costs	966	3,014
Accrued interest expense	492	639
Other accrued expenses	2,175	1,536
Total	$ 21,353	$ 17,026