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Property and Equipment (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Dec. 31, 2014
Property and equipment          
Property and equipment, gross $ 9,978,000   $ 9,978,000   $ 8,738,000
Less accumulated depreciation and amortization (6,768,000)   (6,768,000)   (6,290,000)
Property and equipment, net 3,210,000   3,210,000   2,448,000
Depreciation and amortization expense 162,000 $ 184,000 478,000 $ 529,000  
Computer Equipment          
Property and equipment          
Property and equipment, gross 1,039,000   1,039,000   862,000
Software          
Property and equipment          
Property and equipment, gross 663,000   663,000   254,000
Lab Equipment and Furniture          
Property and equipment          
Property and equipment, gross 5,634,000   5,634,000   5,194,000
Leasehold Improvements          
Property and equipment          
Property and equipment, gross $ 2,642,000   $ 2,642,000   $ 2,428,000