Income Taxes (Details) (USD $)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Current
Federal			$ 14,090,000
State			2,155,000
Total	0	0	16,245,000
Reconciliation of the expected income tax benefit computed using the federal statutory income tax rate to the Company's effective income tax rate
Income tax (benefit) computed at federal statutory tax rate	(32,286,000)	(16,270,000)	(13,419,000)
Permanent items	340,000	396,000	57,000
State taxes	(4,772,000)	(2,487,000)	(2,155,000)
Change in valuation allowance	31,526,000	18,754,000
Uncertain tax position	5,411,000	(64,000)	129,000
Research and development credits	(156,000)		(857,000)
Other	(63,000)	(329,000)
Tax benefit	0	0	(16,245,000)
Pre-tax income from discontinued operations			93,300,000
Income tax expense from discontinued operations			36,800,000
NOL carryforwards	144,300,000
NOL carryforwards after tax effect	58,000,000
Research and development credit carryforwards	4,200,000
Income taxes paid	0	0	0
Deferred tax assets:
Net operating loss carryforward	58,047,000	32,714,000
Deferred rent credit	615,000	477,000
Accrued compensation and non-qualified stock options	1,986,000	59,000
Deferred financing costs	319,000
Depreciation and amortization	337,000	282,000
Research and development credits	4,167,000	3,901,000
Capitalized overhead into inventory (UNICAP 263A)	282,000
Other	151,000	789,000
Valuation allowance	(59,823,000)	(38,222,000)
Net deferred tax asset	6,081,000	0
Deferred tax liability:
Debt discount on convertible notes	(6,081,000)
Net deferred taxes	0	0
Net change in total valuation allowance due to the tax attributes utilized by discontinued operations	21,600,000
Reconciliation of the beginning and ending amount of gross unrecognized tax benefits
Balance at the beginning of the period	688,000	752,000	642,000
Gross increases related to prior-year tax positions	23,000
Gross increases (decrease) related to current-year tax positions	9,117,000	(64,000)	110,000
Balance at the end of the period	$ 9,828,000	$ 688,000	$ 752,000