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Quarterly Financial Information (unaudited) (Tables)
12 Months Ended
Dec. 31, 2013
Quarterly Financial Information (unaudited)  
Schedule of quarterly financial information

Quarterly financial information for fiscal 2013 and 2012 are presented in the following table, in thousands, except per share data, unaudited:

 
  1st Quarter   2nd Quarter   3rd Quarter   4th Quarter  

2013

                         

Revenue

  $ 147   $ 281   $ 1,257   $ 10,334  

Total costs and expenses

    18,055     15,760     18,432     21,691  

Operating loss

    (17,908 )   (15,479 )   (17,175 )   (11,357 )

Net loss

    (18,414 )   (27,357 )   (24,096 )   (22,406 )

Net loss per share, basic and diluted

    (0.60 )   (0.89 )   (0.78 )   (0.65 )

2012

   
 
   
 
   
 
   
 
 

Revenue

  $ 208   $ 91   $ 91   $ 1,090  

Total costs and expenses

    8,086     9,348     12,381     13,834  

Operating loss

    (9,277 )   (10,013 )   (13,482 )   (13,512 )

Net loss

    (9,277 )   (10,013 )   (13,482 )   (13,512 )

Net loss per share, basic and diluted

    (6.05 )   (0.61 )   (0.55 )   (0.51 )