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Summary of Significant Accounting Policies (Details 6)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Series A Preferred Stock
     
Loss per share      
Common stock equivalents excluded in the calculation of diluted loss per share 4,049,863 12,249,998 12,249,998
Warrants to purchase Series A Preferred Stock
     
Loss per share      
Common stock equivalents excluded in the calculation of diluted loss per share 21,090 143,749  
Stock options, Non-Vested Stock Options and ESPP Awards
     
Loss per share      
Common stock equivalents excluded in the calculation of diluted loss per share 256,939 598,109 767,428