Consolidated Statements of Operations (USD $) In Thousands, except Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Consolidated Statements of Operations
Revenues	$ 1,480	$ 803	$ 106
Costs and expenses
Research and development	23,517	30,627	35,149
Selling, general and administrative	20,132	7,928	5,080
Total costs and expenses	43,649	38,555	40,229
Operating loss from continuing operations	(42,169)	(37,752)	(40,123)
Other income (expense):
Interest income	120	31	107
Interest expense	(3,575)	(1,866)
Other income (expense)	(660)	117	542
Total other income (expense)	(4,115)	(1,718)	649
Loss from continuing operations before income tax benefit	(46,284)	(39,470)	(39,474)
Income tax benefit	0	16,245	399
Loss from continuing operations	(46,284)	(23,225)	(39,075)
Discontinued Operations:
Income from discontinued operations, net of tax		2,188	612
Gain on disposal of discontinued operations, net of tax		74,852
Income from discontinued operations		77,040	612
Net (loss) income	(46,284)	53,815	(38,463)
Cumulative dividends on Series A convertible preferred stock	(1,143)	(3,430)	(3,430)
Net (loss) income attributable to common stockholders	$ (47,427)	$ 50,385	$ (41,893)
Basic and diluted
Continuing operations (in dollars per share)	$ (2.72)	$ (16.60)	$ (26.77)
Discontinued operations (in dollars per share)		$ 47.99	$ 0.39
Net (loss) income (in dollars per share)	$ (2.72)	$ 31.39	$ (26.38)
Weighted-average number of common shares:
Basic (in shares)	17,440,910	1,605,324	1,587,968
Diluted (in shares)	17,440,910	1,605,324	1,587,968