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Organization and Nature of Operations (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 12 Months Ended
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2011
Sep. 30, 2011
Jun. 30, 2011
Mar. 31, 2011
Dec. 31, 2012
item
Dec. 31, 2011
Dec. 31, 2010
Organization and Nature of Operations                      
Number of proprietary products in clinical development                 2    
Number of product candidates receiving tentative approval                 1    
Net (loss) income $ (13,512) $ (13,482) $ (10,013) $ (9,277) $ 81,975 $ (9,734) $ (7,377) $ (11,049) $ (46,284) $ 53,815 $ (38,463)
Gain on the sale of TCD, net of taxes                   $ 74,852