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Summary of Significant Accounting Policies (Details 5) (USD $)
9 Months Ended 12 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Dec. 14, 2011
Non-recourse notes issued by TCD
Deferred Financing Costs            
Deferred financing costs $ 142,000   $ 2,054,000 $ 1,291,000   $ 4,400,000
Revenue Recognition            
Maximum duration of contracts under which development revenues have been earned 1 year          
Milestone revenues recorded 200,000 800,000 800,000 0 800,000  
Royalty revenues related to an amendment to a license agreement with Shire plc         $ 36,875,000  
Period from signing the amendment within which one-time payment is committed to be paid by Shire plc         15 days