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Consolidated Statements of Operations (Parenthetical) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Related Party Transaction [Line Items]      
Revenues $ 90,722 $ 151,178 $ 219,463
Collaboration and licensing agreements      
Related Party Transaction [Line Items]      
Revenues 14,059 69,540 134,624
Continuing Operations      
Related Party Transaction [Line Items]      
Revenues 90,722 151,178 219,463
Continuing Operations | Collaboration and licensing agreements      
Related Party Transaction [Line Items]      
Revenues 14,059 69,540 134,624
Continuing Operations | Collaboration and licensing agreements | Related Parties, Aggregated      
Related Party Transaction [Line Items]      
Revenues $ 11,832 $ 55,573 $ 122,485