Segments - Summary of Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Other expenses:
Depreciation and amortization	$ (4,526)	$ (6,668)	$ (10,765)
Gain (loss) from disposals of assets	2	72	(421)
Stock-based compensation expense	(9,471)	(9,888)	(10,206)
Equity in net income (loss) of affiliates	0	0	862
Shares issued for payment of services	553	545	575
Other	0	(2)	(107)
Deconsolidation, Gain (Loss), Amount	(2,915)	0	0
Consolidated loss from continuing operations before income taxes	(128,028)	(96,362)	(79,966)
Operating segments
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	(83,216)	(76,065)	(72,545)
Remove cash paid for capital expenditures net of proceeds from sale of assets	8,524	1,438	1,395
Interest Income	1,418	3,237	133
Operating segments | Add recognition of previously deferred revenue associated with upfront and milestone payments
Segment Reporting Information [Line Items]
Add recognition of previously deferred revenue associated with upfront and milestone payments	0	0	14,561
Corporate And Reconciling Items
Other expenses:
Interest expense	(6)	(468)	(6,774)
Depreciation and amortization	(4,526)	(6,668)	(7,191)
Gain (loss) from disposals of assets	2	72	0
Impairment losses	(40,324)	(10,835)	(1,120)
Stock-based compensation expense	(9,471)	(9,888)	(10,197)
Adjustment related to accrued bonuses paid in equity awards	3,039	3,361	1,698
Equity in net income (loss) of affiliates	0	0	862
Shares issued for payment of services	(553)	(545)	(575)
Other	0	(1)	(107)
Eliminations
Other expenses:
Consolidated loss from continuing operations before income taxes	0	0	(106)
Segment Adjusted EBITDA for reportable segments
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (83,216)	$ (76,065)	$ (72,545)