Share-Based Payments (Tables)

12 Months Ended

Dec. 31, 2024

Share-Based Payment Arrangement [Abstract]

Summary of Stock-based Compensation Expense

Stock-based compensation costs included in the consolidated statements of operations are presented below:

	Year Ended December 31,
	2024		2023		2022
Cost of products and services	$	41	$	72	$	110
Research and development	2,828		2,237		2,188
Selling, general and administrative	6,602		7,579		7,899
Discontinued operations	—		—		9
Total	$	9,471	$	9,888	$	10,206

Summary of Stock Option Activity

Stock option activity was as follows:

	Number of Shares	Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2021	12,260,187	$	14.06	6.79
Granted	4,451,890	2.22
Exercised	(375)	(2.28)
Forfeited	(567,179)	(5.19)
Expired	(943,247)	(22.32)
Balances at December 31, 2022	15,201,276	10.41		6.87
Granted	7,847,869	1.19
Exercised	—	—
Forfeited	(275,250)	(2.65)
Expired	(716,555)	(20.41)
Balances at December 31, 2023	22,057,340	6.90		7.12
Granted	7,361,674	1.40
Exercised	(265,448)	(1.30)
Forfeited	(1,586,732)	(1.72)
Expired	(1,642,100)	(17.10)
Balances at December 31, 2024	25,924,734	5.07		7.05
Exercisable at December 31, 2024	15,384,119	7.42		5.89

Summary of Restricted Stock Unit Activity

RSU and PSU activity was as follows:

	Number of RSUs and PSUs	Weighted Average Grant Date Fair Value		Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2021	468,481	$	8.47	0.33
Granted	1,387,831	2.12
Vested	(1,125,785)	(4.29)
Forfeited	(32,712)	(7.26)
Balances at December 31, 2022	697,815	2.66		0.13
Granted	4,083,777	1.01
Vested	(3,820,058)	(1.27)
Forfeited	—	—
Balances at December 31, 2023	961,534	1.17		0.19
Granted	7,769,484	1.29
Vested	(4,726,961)	(1.37)
Forfeited	—	—
Balances at December 31, 2024	4,004,057	1.16		0.55