Lines of Credit and Long-Term Debt - Long-Term Debt - Additional Information (Details)	1 Months Ended		12 Months Ended
	Sep. 30, 2020 shares	Jul. 31, 2018 USD ($) day $ / shares	Dec. 31, 2022 USD ($) $ / shares	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Mar. 06, 2023 USD ($)	Aug. 18, 2022 USD ($)	Sep. 30, 2018 USD ($)
Debt Instrument [Line Items]
Deferred income taxes			$ (150,000)	$ (167,000)	$ (156,000)
Long-term debt, net of current portion			0	179,882,000
Additional paid-in capital			(1,998,314,000)	(2,022,701,000)
Accumulated deficit			1,868,567,000	1,915,556,000
Restricted Cash							$ 200,000,000
Gain (Loss) on Extinguishment of Debt			961,000	0	0
Interest payable			759,000
Subsequent Event
Debt Instrument [Line Items]
Debt instrument, repurchased face amount						$ 15,460,000
Debt instrument, repurchase amount						$ 15,305,000
Cumulative effect of adoption of ASU 2020-06
Debt Instrument [Line Items]
Long-term debt, net of current portion				18,196,000
Additional paid-in capital				36,868,000
Accumulated deficit				(18,672,000)
Discontinued Operations, Held-for-sale or Disposed of by Sale | Trans Ova
Debt Instrument [Line Items]
Restricted cash, current			43,339,000
Convertible debt
Debt Instrument [Line Items]
Extinguishment of Debt, Amount			156,660,000
Gain (Loss) on Extinguishment of Debt			961,000
Convertible debt | Precigen ActoBio, Inc. | Harvest Intrexon Enterprise Fund I, LP
Debt Instrument [Line Items]
Debt instrument, interest rate, stated percentage								3.00%
Interest expense					$ 616,000
3.5% Convertible Notes Due 2023
Debt Instrument [Line Items]
Aggregate principal amount		$ 200,000,000	$ 43,340,000
Proceeds from long-term debt, net of issuance costs		193,958,000
Debt issuance costs		$ 6,042,000
Debt instrument, interest rate, stated percentage		3.50%
Conversion rate		58.6622
Principal amount used in conversion		$ 1,000
Conversion price (in usd per share) | $ / shares		$ 17.05	$ 17.05
Debt instrument redemption price, percentage		100.00%
Carrying value of convertible debt		$ 143,723,000	$ 43,219,000	$ 179,882,000
Adjustments to additional paid in capital, equity component of convertible debt		50,235,000
Deferred income taxes		$ 13,367,000
Effective interest rate on convertible notes			4.25%
Convertible notes, unamortized discount and issuance costs			$ 121,000
3.5% Convertible Notes Due 2023 | Minimum
Debt Instrument [Line Items]
Common stock price trading days | day		20
Common stock price consecutive trading days | day		30
Percentage of common share price over conversion price for conversion		130.00%
3.5% Convertible Notes Due 2023 | Maximum
Debt Instrument [Line Items]
Common stock price trading days | day		5
Common stock price consecutive trading days | day		5
Debt instrument redemption price, percentage		98.00%
ActoBio Notes
Debt Instrument [Line Items]
Common stock issued upon conversion of long-term debt (in shares) | shares	6,293,402
Harvest Intrexon Enterprise Fund I, LP | Precigen ActoBio, Inc.
Debt Instrument [Line Items]
Aggregate principal amount								$ 30,000,000