Property, Plant and Equipment, Net

12 Months Ended

Dec. 31, 2022

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment, Net

Property, Plant and Equipment, Net

Property, plant and equipment consist of the following:

	December 31,
	2022		2021
Land and land improvements	$	164	$	164
Buildings and building improvements	2,592		2,592
Furniture and fixtures	457		434
Equipment	18,006		16,812
Leasehold improvements	4,333		3,366
Breeding stock	123		36
Computer hardware and software	4,562		4,823
Construction and other assets in progress	531		1,829
	30,768		30,056
Less: Accumulated depreciation and amortization	(23,439)		(21,457)
Property, plant and equipment, net	$	7,329	$	8,599

Depreciation expense was $2,393, $2,866, and $3,049 for the years ended December 31, 2022, 2021, and 2020, respectively.

Recorded impairment losses of $638, $543 and $814 for the years ended December 31, 2022, 2021, and 2020, respectively, are included in impairment of other noncurrent assets on the accompanying consolidated statement of operations and are primarily related to right-of-use assets at certain of the Company's leased locations.