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Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Segment Reporting Information [Line Items]        
Segment Adjusted EBITDA for reportable segments $ (12,071) $ (11,044) $ (30,587) $ (28,743)
Other expenses:        
Depreciation and amortization     (9,044) (10,442)
Gain on disposals of assets     (421) (89)
Stock-based compensation expense (2,125) (2,490) (7,996) (11,462)
Equity in net income (loss) of affiliates     861 (3)
Other     (105) 0
Consolidated net loss from continuing operations before income taxes (7,694) (26,380) (57,798) (84,282)
Operating segments        
Segment Reporting Information [Line Items]        
Remove cash paid for capital expenditures, net of proceeds from sale of assets, and cash paid for investments in affiliates 641 1,138 1,309 1,673
Operating segments | Add recognition of previously deferred revenue associated with upfront and milestone payments        
Segment Reporting Information [Line Items]        
Add recognition of previously deferred revenue associated with upfront and milestone payments 14,561 1,163 16,007 1,849
Corporate And Reconciling Items        
Other expenses:        
Interest expense (2,036) (4,765) (6,137) (13,902)
Depreciation and amortization (1,717) (2,029) (5,470) (6,174)
Gain on disposals of assets 0 (13) 0 (6)
Impairment losses 0 0 (1,120) (543)
Stock-based compensation expense (2,184) (2,422) (7,987) (11,767)
Adjustment related to accrued bonuses paid in equity awards 0 0 1,698 0
Equity in net income (loss) of affiliates 862 0 861 (3)
Other 0 (5) (105) (19)
Unallocated corporate costs        
Other expenses:        
Consolidated net loss from continuing operations before income taxes (5,744) (7,166) (24,718) (24,835)
Eliminations        
Other expenses:        
Consolidated net loss from continuing operations before income taxes (6) (1,237) (1,549) (1,812)
Segment Adjusted EBITDA for reportable segments        
Segment Reporting Information [Line Items]        
Segment Adjusted EBITDA for reportable segments $ (12,071) $ (11,044) $ (30,587) $ (28,743)