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Goodwill and Intangible Assets, Net
 9 Months Ended
Sep. 30, 2022
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets, Net Goodwill and Intangible Assets, Net
The changes in the carrying amount of goodwill for the nine months ended September 30, 2022 were as follows:
Balance at December 31, 2021$37,554 
Impairment(482)
Foreign currency translation adjustments(359)
Balance at September 30, 2022$36,713 
The Company recorded $482 of goodwill impairment related to the total goodwill assigned to one reporting unit within the biopharmaceutical segment during the first quarter of 2022.
The Company had $14,483 and $14,001 of cumulative impairment losses as of September 30, 2022 and December 31, 2021, respectively.
Intangible assets consist of the following as of September 30, 2022:
Gross Carrying AmountAccumulated AmortizationNet
Patents, developed technologies and know-how$75,129 $(32,713)$42,416 
Customer relationships1,600 (1,600)— 
Trademarks200 (200)— 
Total$76,929 $(34,513)$42,416 
Intangible assets consist of the following as of December 31, 2021:
Gross Carrying AmountAccumulated AmortizationNet
Patents, developed technologies and know-how$85,173 $(32,882)$52,291 
Customer relationships1,600 (1,600)— 
Trademarks200 (200)— 
Total$86,973 $(34,682)$52,291 
Amortization expense was $1,151 and $1,315 for the three months ended September 30, 2022 and 2021, respectively, and $3,637 and $3,990 for the nine months ended September 30, 2022 and 2021, respectively.