Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (2,665)	$ (627)
Other expenses:
Depreciation and amortization	(3,292)	(3,523)
Loss on disposals of assets	(125)	343
Stock-based compensation expense	(3,562)	(5,415)
Equity in net loss of affiliates	(1)	(3)
Other	0	(1)
Consolidated net loss from continuing operations before income taxes	(19,309)	(21,896)
Add recognition of previously deferred revenue associated with upfront and milestone payments
Segment Reporting Information [Line Items]
Add recognition of previously deferred revenue associated with upfront and milestone payments	0	66
Operating segments
Segment Reporting Information [Line Items]
Remove cash paid for capital expenditures, net of proceeds from sale of assets, and cash paid for investments in affiliates	1,314	597
Operating segments | Add recognition of previously deferred revenue associated with upfront and milestone payments
Segment Reporting Information [Line Items]
Add recognition of previously deferred revenue associated with upfront and milestone payments	1,446	307
Corporate And Reconciling Items
Other expenses:
Interest expense	(2,069)	(4,539)
Depreciation and amortization	(3,292)	(3,523)
Loss on disposals of assets	(125)	(121)
Impairment losses	(482)	0
Stock-based compensation expense	(3,562)	(5,415)
Adjustment related to accrued bonuses paid in equity awards	1,698	0
Equity in net loss of affiliates	(1)	(3)
Other	0	(7)
Unallocated corporate costs
Other expenses:
Consolidated net loss from continuing operations before income taxes	(10,060)	(8,194)
Eliminations
Other expenses:
Consolidated net loss from continuing operations before income taxes	(1,511)	(371)
Segment Adjusted EBITDA for reportable segments
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (2,665)	$ (627)