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Goodwill and Intangible Assets, Net
12 Months Ended
Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets, Net Goodwill and Intangible Assets, Net
The changes in the carrying amount of goodwill for the years ended December 31, 2021 and 2020, are as follows:
20212020
Beginning of year$54,363 $54,119 
Foreign currency translation adjustments(215)244 
End of year$54,148 $54,363 
The Company had $43,643 of cumulative goodwill impairment losses as of December 31, 2021 and 2020.
For the year ended December 31, 2019, during the Company's annual goodwill impairment test, the Company determined it was more-likely-than-not that the fair value of the Trans Ova reporting unit was less than its carrying amount. As a result, the Company compared the carrying amount of the Trans Ova reporting unit to the fair value and determined the carrying amount exceeded the fair value resulting in a $29,642 goodwill impairment charge for the excess carrying value. Additionally, the Company recorded $178 of goodwill impairment in conjunction with the closing of two of its reporting units during the third quarter of 2019.
See Note 18 for information regarding goodwill by reportable segment.
Intangible assets consist of the following as of December 31, 2021: 
Weighted Average Useful Life (Years)Gross Carrying AmountAccumulated AmortizationNet
Patents, developed technologies and know-how15.9$91,373 $(38,630)$52,743 
Customer relationships6.410,850 (10,252)598 
Trademarks8.45,900 (5,126)774 
Total$108,123 $(54,008)$54,115 
Intangible assets consist of the following as of December 31, 2020: 
Gross Carrying AmountAccumulated AmortizationNet
Patents, developed technologies and know-how$96,927 $(34,412)$62,515 
Customer relationships10,850 (9,340)1,510 
Trademarks5,900 (4,529)1,371 
Total$113,677 $(48,281)$65,396 
Amortization expense was $7,559, $7,593, and $7,920 for the years ended December 31, 2021, 2020, and 2019, respectively. Estimated aggregate amortization expense for definite lived intangible assets is expected to be as follows:
2022$6,597 
20235,431 
20245,121 
20255,108 
20265,108 
Thereafter26,750 
Total$54,115