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Related Party Transactions - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jan. 31, 2020
Dec. 31, 2019
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Third Security, LLC            
Related Party Transaction [Line Items]            
Expense for services     $ 43 $ 56 $ 89 $ 132
Sublease rental income     $ 20 $ 18 $ 61 $ 64
Castle Creek Biosciences, Inc.            
Related Party Transaction [Line Items]            
Proceeds from sale and maturity of other investments   $ 1,280        
Proceeds from convertible notes receivable and investment in preferred stock $ 3,311          
Third Security, LLC | Executive Chairman            
Related Party Transaction [Line Items]            
Ownership interest     100.00%   100.00%