Segments - Information by Reportable Segment (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Segment Reporting Information [Line Items]
Revenues from external customers	$ 23,583	$ 18,299	$ 83,845	$ 73,720
Segment Adjusted EBITDA	(10,478)	(26,658)	(35,558)	(66,858)
PGEN Therapeutics
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(6,739)	(5,953)	(19,356)	(20,789)
ActoBio
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(1,602)	(4,634)	(4,727)	(11,196)
MBP Titan
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(1,765)	(9,024)	(15,728)	(26,238)
Trans Ova
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(1,606)	(5,560)	3,723	(2,854)
Human Biotherapeutics
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(420)	(142)	(2,253)	(719)
All Other
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	1,654	(1,345)	2,783	(5,062)
Operating segments
Segment Reporting Information [Line Items]
Revenues from external customers	23,583	18,299	83,791	73,573
Revenues	25,630	20,947	90,037	82,515
Operating segments | PGEN Therapeutics
Segment Reporting Information [Line Items]
Revenues from external customers	164	444	542	2,174
Revenues	2,156	2,757	6,249	9,264
Operating segments | ActoBio
Segment Reporting Information [Line Items]
Revenues from external customers	2,823	231	3,053	813
Revenues	2,823	237	3,050	1,314
Operating segments | MBP Titan
Segment Reporting Information [Line Items]
Revenues from external customers	0	1,117	0	3,813
Revenues	0	1,117	7	3,815
Operating segments | Trans Ova
Segment Reporting Information [Line Items]
Revenues from external customers	15,228	13,981	55,858	53,307
Revenues	15,283	14,238	56,112	54,511
Operating segments | Human Biotherapeutics
Segment Reporting Information [Line Items]
Revenues from external customers	2,394	402	16,967	3,247
Revenues	2,394	402	16,967	3,247
Operating segments | All Other
Segment Reporting Information [Line Items]
Revenues from external customers	2,974	2,124	7,371	10,219
Revenues	2,974	2,196	7,652	10,364
Intersegment revenues
Segment Reporting Information [Line Items]
Revenues	2,047	2,648	6,246	8,942
Intersegment revenues | PGEN Therapeutics
Segment Reporting Information [Line Items]
Revenues	1,992	2,313	5,707	7,090
Intersegment revenues | ActoBio
Segment Reporting Information [Line Items]
Revenues	0	6	(3)	501
Intersegment revenues | MBP Titan
Segment Reporting Information [Line Items]
Revenues	0	0	7	2
Intersegment revenues | Trans Ova
Segment Reporting Information [Line Items]
Revenues	55	257	254	1,204
Intersegment revenues | Human Biotherapeutics
Segment Reporting Information [Line Items]
Revenues	0	0	0	0
Intersegment revenues | All Other
Segment Reporting Information [Line Items]
Revenues	$ 0	$ 72	$ 281	$ 145