Segments - Information by Reportable Segment (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Segment Reporting Information [Line Items]
Revenues from external customers	$ 30,424	$ 32,836	$ 60,262	$ 55,421
Segment Adjusted EBITDA	(5,362)	(18,680)	(25,080)	(40,200)
PGEN Therapeutics
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(5,698)	(7,467)	(12,617)	(14,836)
ActoBio
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(1,135)	(4,124)	(3,125)	(6,562)
MBP Titan
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(5,199)	(9,188)	(13,963)	(17,214)
Trans Ova
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	6,528	4,932	5,329	2,706
Human Biotherapeutics
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(495)	(354)	(1,833)	(577)
All Other
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	637	(2,479)	1,129	(3,717)
Operating segments
Segment Reporting Information [Line Items]
Revenues from external customers	30,410	32,797	60,208	55,274
Revenues	32,109	35,997	64,407	61,568
Operating segments | PGEN Therapeutics
Segment Reporting Information [Line Items]
Revenues from external customers	218	549	378	1,730
Revenues	1,830	2,961	4,093	6,507
Operating segments | ActoBio
Segment Reporting Information [Line Items]
Revenues from external customers	32	181	230	582
Revenues	29	233	227	1,077
Operating segments | MBP Titan
Segment Reporting Information [Line Items]
Revenues from external customers	0	1,215	0	2,696
Revenues	0	1,217	7	2,698
Operating segments | Trans Ova
Segment Reporting Information [Line Items]
Revenues from external customers	23,845	24,392	40,630	39,326
Revenues	23,935	25,066	40,829	40,273
Operating segments | Human Biotherapeutics
Segment Reporting Information [Line Items]
Revenues from external customers	4,210	2,462	14,573	2,845
Revenues	4,210	2,462	14,573	2,845
Operating segments | All Other
Segment Reporting Information [Line Items]
Revenues from external customers	2,105	3,998	4,397	8,095
Revenues	2,105	4,058	4,678	8,168
Intersegment revenues
Segment Reporting Information [Line Items]
Revenues	1,699	3,200	4,199	6,294
Intersegment revenues | PGEN Therapeutics
Segment Reporting Information [Line Items]
Revenues	1,612	2,412	3,715	4,777
Intersegment revenues | ActoBio
Segment Reporting Information [Line Items]
Revenues	(3)	52	(3)	495
Intersegment revenues | MBP Titan
Segment Reporting Information [Line Items]
Revenues	0	2	7	2
Intersegment revenues | Trans Ova
Segment Reporting Information [Line Items]
Revenues	90	674	199	947
Intersegment revenues | Human Biotherapeutics
Segment Reporting Information [Line Items]
Revenues	0	0	0	0
Intersegment revenues | All Other
Segment Reporting Information [Line Items]
Revenues	$ 0	$ 60	$ 281	$ 73