Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	$ (19,718)	$ (21,520)
Other expenses:
Depreciation and amortization	(4,810)	(6,577)
Stock-based compensation expense	(4,372)	(9,054)
Equity in net loss of affiliates	(389)	(1,640)
Other	(239)	(235)
Loss before income taxes	(29,902)	(52,913)
Operating segments
Segment Reporting Information [Line Items]
Remove cash paid for capital expenditures and investments in affiliates	2,741	3,512
Corporate And Reconciling Items
Other expenses:
Interest expense	(4,592)	(4,305)
Depreciation and amortization	(4,810)	(5,344)
Stock-based compensation expense	(5,718)	(8,248)
Adjustment related to bonuses paid in equity awards	2,833	0
Equity in net loss of affiliates	(351)	(748)
Other	9	0
Unallocated corporate costs
Other expenses:
Loss before income taxes	(10,182)	(18,022)
Eliminations
Other expenses:
Loss before income taxes	(2,587)	(2,850)
Segment Adjusted EBITDA for reportable segments
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(20,210)	(20,282)
All Other
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	492	(1,238)
Upfront and milestone payments | Operating segments
Segment Reporting Information [Line Items]
Add recognition of previously deferred revenue associated with upfront and milestone payments	$ 12,473	$ 4,612