Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	$ (32,940)	$ (28,948)	$ (66,219)	$ (58,348)
Other expenses:
Interest expense	(4,358)	(142)	(8,669)	(241)
Depreciation and amortization			(12,690)	(16,881)
Stock-based compensation expense	(61)	(8,846)	(9,115)	(20,208)
Equity in net loss of affiliates	(1,747)	(4,550)	(3,387)	(7,010)
Loss before income taxes	(39,456)	(67,956)	(102,170)	(119,451)
Operating segments
Segment Reporting Information [Line Items]
Remove cash paid for capital expenditures and investments in affiliates	14,695	9,668	25,985	20,049
Corporate And Reconciling Items
Other expenses:
Interest expense	(4,358)	(142)	(8,669)	(241)
Depreciation and amortization	(6,113)	(8,499)	(12,690)	(16,881)
Stock-based compensation expense	(61)	(8,846)	(9,115)	(20,208)
Equity in net loss of affiliates	(1,747)	(4,550)	(3,387)	(7,010)
Unallocated corporate costs
Other expenses:
Loss before income taxes	(13,032)	(33,122)	(32,978)	(52,673)
Eliminations
Other expenses:
Loss before income taxes	(3,162)	(571)	(6,012)	(1,038)
Reportable segments
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(22,880)	(18,770)	(48,725)	(36,314)
All Other
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA	(10,060)	(10,178)	(17,494)	(22,034)
Upfront and Milestone Payments | Operating segments
Segment Reporting Information [Line Items]
Add recognition of previously deferred revenue associated with upfront and milestone payments	$ 7,262	$ 7,054	$ 10,915	$ 16,899