Collaboration and Licensing Revenue - Summary of Deferred Revenue (Details) - USD ($) $ in Thousands	Mar. 31, 2019	Dec. 31, 2018
Contract With Customer, Asset And Liability [Line Items]
Deferred revenue	$ 71,191	$ 69,764
Current portion of deferred revenue	17,149	15,554
Long-term portion of deferred revenue	54,042	54,210
Collaboration and licensing agreements
Contract With Customer, Asset And Liability [Line Items]
Deferred revenue	65,135	63,284
Prepaid product and service revenues
Contract With Customer, Asset And Liability [Line Items]
Deferred revenue	3,157	2,933
Other
Contract With Customer, Asset And Liability [Line Items]
Deferred revenue	$ 2,899	$ 3,547