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Consolidated Statements of Operations (Parenthetical) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Related Party Transaction [Line Items]    
Collaboration and licensing revenues $ 24,025 $ 33,065
Related Parties, Aggregated    
Related Party Transaction [Line Items]    
Collaboration and licensing revenues $ 19,815 $ 28,887