Share-Based Payments (Tables)

3 Months Ended

Mar. 31, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Stock-Based Compensation Costs

Stock-based compensation costs included in the consolidated statements of operations are presented below:

	Three Months Ended   March 31,
	2017		2016
Cost of products	$	26	$	20
Cost of services	78		68
Research and development	2,193		2,565
Selling, general and administrative	5,597		10,535
Total	$	7,894	$	13,188

Schedule of Stock Option Activity

Stock option activity was as follows:

	Number of Shares		Weighted Average Exercise Price			Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2016	11,640,383		$	31.25		8.21
Granted	3,020,950		21.32
Adjustment due to dividend (Note 13)	46,766		31.11
Exercised	(10,343	)	(16.93		)
Forfeited	(2,058,040	)	(29.89		)
Expired	(7,209	)	(36.72		)
Balances at March 31, 2017	12,632,507		28.99			8.19
Exercisable at March 31, 2017	4,444,346		28.73			6.85