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Consolidated Statements of Operations Consolidated Statements of Operations (Parenthetical) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Related Party Transaction [Line Items]      
Collaboration and licensing revenues $ 109,871 $ 87,821 $ 45,212
Related Parties, Aggregated      
Related Party Transaction [Line Items]      
Collaboration and licensing revenues $ 93,792 $ 77,354 $ 41,030