Summary of Significant Accounting Policies - Additional Information (Details) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016 USD ($)	Jun. 30, 2015 USD ($)	Jun. 30, 2016 USD ($) segment	Jun. 30, 2015 USD ($)	Dec. 31, 2015 USD ($)
Organization And Significant Accounting Policies [Line Items]
Fair value of financial assets measured at fair value on a recurring basis	$ 325,186		$ 325,186		$ 291,762
Maximum risk of loss related to the identified VIEs	137,920		$ 137,920		3,598
Number of segments | segment			1
Property, plant and equipment, net	46,659		$ 46,659		42,739
Revenues	52,501	$ 44,891	95,939	$ 78,740
Foreign Countries
Organization And Significant Accounting Policies [Line Items]
Property, plant and equipment, net	5,666		5,666		3,877
Revenues	2,680	925	5,176	2,263
Equity securities
Organization And Significant Accounting Policies [Line Items]
Fair value of financial assets measured at fair value on a recurring basis	$ 39,020		$ 39,020		$ 83,653
Oragenics, Inc.
Organization And Significant Accounting Policies [Line Items]
Company's ownership percentage	29.50%		29.50%		30.70%
Oragenics, Inc. | Equity securities
Organization And Significant Accounting Policies [Line Items]
Fair value of financial assets measured at fair value on a recurring basis	$ 6,626		$ 6,626		$ 16,601
Unrealized appreciation (depreciation) in fair value of equity securities	$ (4,797)	$ 2,943	$ (11,142)	$ 3,879