Summary of Significant Accounting Policies - Additional Information (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2016 USD ($) segment joint_venture	Mar. 31, 2015 USD ($)	Dec. 31, 2015 USD ($)
Organization And Significant Accounting Policies [Line Items]
Number of strategic joint ventures | joint_venture	6
Fair value of financial assets measured at fair value on a recurring basis	$ 251,692		$ 291,762
Unrealized appreciation (depreciation) in fair value of equity securities	(22,331)	$ 115,454
Maximum risk of loss related to the identified VIEs	$ 15,600		3,598
Number of segments | segment	1
Property, plant and equipment, net	$ 44,673		42,739
Revenues	43,438	33,849
Foreign Countries
Organization And Significant Accounting Policies [Line Items]
Property, plant and equipment, net	4,817		3,877
Revenues	2,496	1,338
Equity securities
Organization And Significant Accounting Policies [Line Items]
Fair value of financial assets measured at fair value on a recurring basis	$ 61,322		$ 83,653
Oragenics, Inc.
Organization And Significant Accounting Policies [Line Items]
Company's ownership percentage	30.50%		30.70%
Oragenics, Inc. | Equity securities
Organization And Significant Accounting Policies [Line Items]
Fair value of financial assets measured at fair value on a recurring basis	$ 10,256		$ 16,601
Unrealized appreciation (depreciation) in fair value of equity securities	$ (6,345)	$ 936