XML 122 R108.htm IDEA: XBRL DOCUMENT v3.3.1.900
Net Loss per Share - Potentially Dilutive Securities Excluded from Calculation of Net Loss per Share (Detail) - shares
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 11,238,247 8,676,027 3,255,052
Options      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 11,043,528 8,323,544 2,840,648
Warrants      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 194,719 352,483 414,404