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Stock Option Plans (Tables)
 12 Months Ended
Dec. 31, 2014
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Stock Based Compensation Expense Allocation
Stock-based compensation costs included in the consolidated statements of operations are presented below:
 
Year Ended December 31,
 
2014
 
2013
 
2012
Cost of products
$
14

 
$
—

 
$
—

Cost of services
142

 
—

 
—

Research and development
4,817

 
514

 
377

Selling, general and administrative
16,876

 
2,407

 
1,081

Total
$
21,849

 
$
2,921

 
$
1,458
Summary of Assumptions Used in Pricing Model
The assumptions used in the Black-Scholes option pricing model for the years ended December 31, 2014, 2013 and 2012 are set forth below:
 
2014
 
2013
 
2012
Valuation assumptions
 
 
 
 
 
Expected dividend yield
0%
 
0%
 
0%
Expected volatility
62%—64%
 
73%—75%
 
71%—76%
Expected term (years)
6.25
 
6.25
 
6.00
Risk-free interest rate
1.82%—2.14%
 
0.96%—1.86%
 
0.80%—1.10%
Schedule of Stock Option Activity
Stock option activity was as follows:
 
Number of
Shares
 
Weighted
Average
Exercise
Price
 
Weighted
Average
Remaining
Contractual
Term
Balances at December 31, 2011
3,614,530

 
$
5.22

 
6.67
Granted
548,571

 
7.12

 
 
Exercised
(194,570
)
 
(2.43
)
 
 
Forfeited
(1,210,857
)
 
(6.30
)
 
 
Expired
(444,148
)
 
(2.29
)
 
 
Balances at December 31, 2012
2,313,526

 
5.90

 
7.87
Granted
989,709

 
13.06

 
 
Exercised
(88,764
)
 
(6.04
)
 
 
Forfeited
(335,746
)
 
(6.94
)
 
 
Expired
(38,077
)
 
(5.17
)
 
 
Balances at December 31, 2013
2,840,648

 
8.27

 
7.75
Granted
7,655,050

 
27.51

 
 
Exercised
(315,964
)
 
(4.80
)
 
 
Forfeited
(1,855,578
)
 
(24.00
)
 
 
Expired
(612
)
 
(7.12
)
 
 
Balances at December 31, 2014
8,323,544

 
22.59

 
8.64
Exercisable at December 31, 2014
1,448,434

 
8.27

 
6.25
Vested and Expected to Vest at December 31, 2014(1)
6,742,605

 
21.78

 
8.50

(1)
The number of stock options expected to vest takes into account an estimate of expected forfeitures.
Summary of Additional Information About Stock Options
The following table summarizes additional information about stock options outstanding as of December 31, 2014:
 
 
 
 
Options Outstanding
 
Options Exercisable
Range of Exercise Prices
 
Number of
Options
 
Weighted Average Exercise Price
 
Weighted
Average
Remaining
Life
(Years)
 
Aggregate
Intrinsic
Value
 
Number of
Options
 
Weighted Average Exercise Price
 
Weighted
Average
Remaining
Life
(Years)
 
Aggregate
Intrinsic
Value
$
0.39

—
$
9.67

 
1,747,494

 
$
6.49

 
6.25
 
$
36,772

 
1,293,184

 
$
6.07

 
5.90
 
$
27,746

$
15.39

—
$
22.77

 
2,603,300

 
21.74

 
9.32
 
15,084

 
57,000

 
19.77

 
9.05
 
442

$
24.73

—
$
28.69

 
260,750

 
26.21

 
9.74
 
363

 
8,250

 
28.25

 
8.63
 
1

$
29.95

 
 
 
1,000,000

 
29.95

 
9.21
 
—

 
—

 
—

 
0.00
 
—

$
30.72

 
 
 
2,712,000

 
30.72

 
9.22
 
—

 
90,000

 
30.72

 
9.22
 
—

 
 
 
 
8,323,544

 
$
22.59

 
8.64
 
$
52,219

 
1,448,434

 
$
8.27

 
6.25
 
$
28,189

The following table summarizes additional information about stock options outstanding as of December 31, 2013:
 
 
 
 
Options Outstanding
 
Options Exercisable
Range of Exercise Prices
 
Number of
Options
 
Weighted Average Exercise Price
 
Weighted
Average
Remaining
Life
(Years)
 
Aggregate
Intrinsic
Value
 
Number of
Options
 
Weighted Average Exercise Price
 
Weighted
Average
Remaining
Life
(Years)
 
Aggregate
Intrinsic
Value
$
0.39

—
$
5.91

 
658,051

 
$
3.15

 
4.96
 
$
13,592

 
571,116

 
$
2.78

 
4.63
 
$
12,003

$
7.12

 
 
 
1,194,887

 
7.12

 
7.80
 
19,931

 
546,805

 
7.12

 
7.77
 
9,121

$
9.67

 
 
 
701,710

 
9.67

 
9.41
 
9,915

 
107,142

 
9.67

 
9.41
 
1,514

$
19.83

 
 
 
225,500

 
19.83

 
9.96
 
895

 
—

 
—

 
0.00
 
—

$
26.76

—
$
28.69

 
60,500

 
27.33

 
9.67
 
—

 
2,500

 
28.69

 
9.62
 
—

 
 
 
 
2,840,648

 
$
8.27

 
7.75
 
$
44,333

 
1,227,563

 
$
5.37

 
6.44
 
$
22,638