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Collaboration Revenue - Additional Information (Detail) (USD $)
In Thousands, except Share data, unless otherwise specified
0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 0 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 0 Months Ended 0 Months Ended
Jul. 26, 2013
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Dec. 31, 2013
Jun. 30, 2014
Upfront and Milestone Payments
Jun. 30, 2013
Upfront and Milestone Payments
Jun. 30, 2014
Upfront and Milestone Payments
Jun. 30, 2013
Upfront and Milestone Payments
Dec. 31, 2013
Upfront and Milestone Payments
Jun. 30, 2014
Research And Development Services
Jun. 30, 2013
Research And Development Services
Jun. 30, 2014
Research And Development Services
Jun. 30, 2013
Research And Development Services
Aug. 06, 2012
Synthetic Biologics Field Two ECC
Aug. 06, 2012
Synthetic Biologics Field Two ECC
Jun. 30, 2014
Synthetic Biologics, Inc.
Jun. 30, 2013
Synthetic Biologics, Inc.
Jun. 30, 2014
Synthetic Biologics, Inc.
Jun. 30, 2013
Synthetic Biologics, Inc.
Jun. 30, 2014
Synthetic Biologics, Inc.
Upfront and Milestone Payments
Jun. 30, 2013
Synthetic Biologics, Inc.
Upfront and Milestone Payments
Jun. 30, 2014
Synthetic Biologics, Inc.
Upfront and Milestone Payments
Jun. 30, 2013
Synthetic Biologics, Inc.
Upfront and Milestone Payments
Jun. 30, 2014
Synthetic Biologics, Inc.
Research And Development Services
Jun. 30, 2013
Synthetic Biologics, Inc.
Research And Development Services
Jun. 30, 2014
Synthetic Biologics, Inc.
Research And Development Services
Jun. 30, 2013
Synthetic Biologics, Inc.
Research And Development Services
Dec. 17, 2012
Synthetic Biologics, Inc.
Research And Development Services
Jun. 05, 2012
Oragenics ECC
Jun. 05, 2012
Oragenics ECC
Sep. 30, 2013
Oragenics Second ECC
Sep. 30, 2013
Oragenics Second ECC
Apr. 30, 2013
Fibrocell Science, Inc.
Oct. 05, 2012
Fibrocell Science, Inc.
Jun. 30, 2014
Fibrocell Science, Inc.
Jun. 30, 2013
Fibrocell Science, Inc.
Jun. 30, 2014
Fibrocell Science, Inc.
Jun. 30, 2013
Fibrocell Science, Inc.
Oct. 05, 2012
Fibrocell Science, Inc.
Jun. 30, 2014
Fibrocell Science, Inc.
Upfront and Milestone Payments
Jun. 30, 2013
Fibrocell Science, Inc.
Upfront and Milestone Payments
Jun. 30, 2014
Fibrocell Science, Inc.
Upfront and Milestone Payments
Jun. 30, 2013
Fibrocell Science, Inc.
Upfront and Milestone Payments
Jun. 30, 2014
Fibrocell Science, Inc.
Research And Development Services
Jun. 30, 2013
Fibrocell Science, Inc.
Research And Development Services
Jun. 30, 2014
Fibrocell Science, Inc.
Research And Development Services
Jun. 30, 2013
Fibrocell Science, Inc.
Research And Development Services
Mar. 29, 2013
Genopaver, LLC
Jun. 30, 2014
Genopaver, LLC
Jun. 30, 2013
Genopaver, LLC
Jun. 30, 2014
Genopaver, LLC
Jun. 30, 2013
Genopaver, LLC
Jun. 30, 2014
Genopaver, LLC
Upfront and Milestone Payments
Jun. 30, 2013
Genopaver, LLC
Upfront and Milestone Payments
Jun. 30, 2014
Genopaver, LLC
Upfront and Milestone Payments
Jun. 30, 2013
Genopaver, LLC
Upfront and Milestone Payments
Jun. 30, 2014
Genopaver, LLC
Research And Development Services
Jun. 30, 2013
Genopaver, LLC
Research And Development Services
Jun. 30, 2014
Genopaver, LLC
Research And Development Services
Jun. 30, 2013
Genopaver, LLC
Research And Development Services
Feb. 14, 2013
AquaBounty ECC
Mar. 26, 2014
Intrexon Energy Partners, LLC
Jun. 30, 2014
Intrexon Energy Partners, LLC
Jun. 30, 2014
Intrexon Energy Partners, LLC
Jun. 30, 2014
Intrexon Energy Partners, LLC
Upfront and Milestone Payments
Jun. 30, 2014
Intrexon Energy Partners, LLC
Upfront and Milestone Payments
Jun. 30, 2014
Intrexon Energy Partners, LLC
Research And Development Services
Jun. 30, 2014
Intrexon Energy Partners, LLC
Research And Development Services
Jan. 06, 2011
Ziopharm Oncology, Inc.
Jun. 30, 2014
Ziopharm Oncology, Inc.
Jun. 30, 2013
Ziopharm Oncology, Inc.
Jun. 30, 2014
Ziopharm Oncology, Inc.
Jun. 30, 2013
Ziopharm Oncology, Inc.
Jan. 06, 2011
Ziopharm Oncology, Inc.
Jun. 30, 2014
Ziopharm Oncology, Inc.
Upfront and Milestone Payments
Jun. 30, 2013
Ziopharm Oncology, Inc.
Upfront and Milestone Payments
Jun. 30, 2014
Ziopharm Oncology, Inc.
Upfront and Milestone Payments
Jun. 30, 2013
Ziopharm Oncology, Inc.
Upfront and Milestone Payments
Jun. 30, 2014
Ziopharm Oncology, Inc.
Research And Development Services
Jun. 30, 2013
Ziopharm Oncology, Inc.
Research And Development Services
Jun. 30, 2014
Ziopharm Oncology, Inc.
Research And Development Services
Jun. 30, 2013
Ziopharm Oncology, Inc.
Research And Development Services
Nov. 18, 2011
Synthetic Biologics Field One ECC
Nov. 18, 2011
Synthetic Biologics Field One ECC
Sep. 30, 2013
S & I Ophthalmic, LLC
Jun. 30, 2014
S & I Ophthalmic, LLC
Jun. 30, 2014
S & I Ophthalmic, LLC
Jun. 30, 2014
S & I Ophthalmic, LLC
Research And Development Services
Jun. 30, 2014
S & I Ophthalmic, LLC
Research And Development Services
Dec. 18, 2013
OvaXon, LLC
Jun. 30, 2014
OvaXon, LLC
Jun. 30, 2014
OvaXon, LLC
Jun. 30, 2014
OvaXon, LLC
Research And Development Services
Jun. 30, 2014
OvaXon, LLC
Research And Development Services
Oct. 05, 2012
Upfront
Synthetic Biologics Field Two ECC
Upfront and Milestone Payments
Jun. 05, 2012
Upfront
Oragenics ECC
Upfront and Milestone Payments
Dec. 18, 2013
Upfront
Oragenics Second ECC
Upfront and Milestone Payments
Sep. 30, 2013
Upfront
Oragenics Second ECC
Upfront and Milestone Payments
Oct. 05, 2012
Upfront
Fibrocell Science, Inc.
Upfront and Milestone Payments
Mar. 29, 2013
Upfront
Genopaver, LLC
Upfront and Milestone Payments
Mar. 26, 2014
Upfront
Intrexon Energy Partners, LLC
Upfront and Milestone Payments
Jan. 06, 2011
Upfront
Ziopharm Oncology, Inc.
Upfront and Milestone Payments
Jan. 06, 2011
Upfront
Ziopharm Oncology ECC Separate Unit of Accounting
Upfront and Milestone Payments
Jan. 06, 2011
Upfront
Ziopharm Oncology ECC Unit of Accounting One
Upfront and Milestone Payments
Nov. 18, 2011
Upfront
Synthetic Biologics Field One ECC
Upfront and Milestone Payments
Jan. 10, 2014
Supplemental Upfront
Fibrocell Science, Inc.
Upfront and Milestone Payments
Jun. 28, 2013
Supplemental Upfront
Fibrocell Science, Inc.
Upfront and Milestone Payments
Oct. 24, 2012
Milestone One
Ziopharm Oncology, Inc.
Upfront and Milestone Payments
Collaboration Agreements [Line Items]                                                                                                                                                                                                                            
Collaborative arrangement consideration received, shares                                                                                                                                                                                                 3,552,210 4,392,425   1,348,000 1,317,520     3,636,926     3,123,558 1,024,590 1,243,781 3,636,926
Collaborative arrangement consideration received, value                                                                                                                                                                                                 $ 7,815 $ 6,588   $ 3,503 $ 7,576 $ 3,000 $ 25,000 $ 17,457     $ 1,687 $ 5,225 $ 7,612 $ 18,330
Collaboration revenue   11,764 6,674 19,601 10,538   2,517 2,751 4,399 3,888   9,247 3,923 15,202 6,650     193 1,980 552 2,550 163 1,666 325 1,861 30 314 227 689               1,331 773 2,641 1,361   448 158 896 316 883 615 1,745 1,045   491 281 981 281 68 68 137 68 423 213 844 213     1,835 1,835 625 625 1,210 1,210   4,341 2,935 7,021 5,009   644 644 1,288 1,288 3,697 2,291 5,733 3,721       607 1,486 607 1,486   579 748 579 748                 1,115          
Deferred revenue   99,453   99,453   73,571 98,233   98,233   72,207                                     2,500                                                                                                                                                       16,342        
Percent of shares outstanding at the date of achievement of future milestone                                                               1.00%                                                                                       7.495%                   9.995%                                                
Royalty rate as a percentage of net profit                                                             25.00%                                                                               50.00%                           50.00%                                                  
Required notice period for voluntary termination of collaborative agreement                               90 days                             90 days   90 days     90 days                           90 days                           90 days             90 days                           90 days   90 days         90 days                                    
Consideration to be received upon achievement of future milestone 1                                 2,000                                 2,000                                                                                                                                                        
Consideration to be received upon achievement of future milestone 2                                 3,000                                 5,000                                                                                                                                                        
Field expansion fee                                 2,000                                                                                                                                                                                          
Percentage of shares outstanding at the date of achievement of future milestone 2                                                               1.50%                                                                                                                                                            
Percentage of shares outstanding at the date of achievement of future milestone 3                                                               2.00%                                                                                                                                                            
Percentage of shares outstanding at the date of achievement of future milestone 4                                                               2.50%                                                                                                                                                            
Percentage of shares outstanding at the date of achievement of future milestone 5                                                               3.00%                                                                                                                                                            
Maturity date of promissory note                                                                                                                                                                                                       December 31, 2013                    
Collaborative arrangement consideration received, value of convertible promissory note                                                                                                                                                                                                       1,956                    
Consideration to be received upon achievement of future milestone 3                                                                   10,000                                                                                                                                                        
Royalty rate as a percentage of net sales, tier 1                                                                 10.00%     7.00%                                                                                                                                                    
Conversion of promissory note into Common stock                                                                                                                                                                                                     698,241                      
Reverse stock split ratio 1-for-1.75                                                                   1-for-25                                                                                                                                                      
Reverse stock split ratio 0.57143                                                                   0.04                                                                                                                                                      
Royalty rate as a percentage of net sales, tier 2                                                                       14.00%                                                                                                                                                    
Royalty rate of savings from improvement                                                                       33.00%                                                                                                                                                    
Level of net sales at which royalty rate changes to tier 2                                                                                 $ 25,000                                                                                                                                          
Royalty rate as a percentage of gross profit                                                                                                                             16.66%