X0306 4 2018-07-03 0 0001356090 INTREXON CORP XON 0001091823 KIRK RANDAL J C/O THIRD SECURITY, LLC 1881 GROVE AVENUE RADFORD VA 24141 1 1 1 0 Chief Executive Officer Common Stock 2018-07-03 4 P 0 6357517 13.37 A 14140139 I by Kapital Joe Common Stock 2018-07-03 4 P 0 1121914 13.37 A 15937319 I by R.J. Kirk DOT Common Stock 1186808 I by Third Security Common Stock 8325000 I by TSCP V Common Stock 311287 I by Staff 2001 Common Stock 1403 I by Lotus Common Stock 139052 I by JPK 2008 Common Stock 140007 I by MGK 2008 Common Stock 114181 I by ZSK 2008 Common Stock 720562 I by JPK 2009 Common Stock 850355 I by MGK 2009 Common Stock 75684 I by ZSK 2009 Common Stock 843044 I by JPK 2012 Common Stock 135033 I by Kellie L. Banks LTT Common Stock 118266 I by Senior Staff 2006 Common Stock 59133 I by Staff 2006 Common Stock 19711 I by Incentive 2006 Common Stock 5483957 I by Mascara Kaboom Common Stock 58800 I by Sr. Staff Common Stock 213805 I by ADC 2010 Common Stock 940426 I by MGK 2011 Common Stock 1356648 I by Senior Staff 2008 Common Stock 1356648 I by Staff 2010 Common Stock 678323 I by Incentive 2010 Common Stock 13340645 I by NRM VI Holdings Common Stock 243001 I by NRM VII Holdings On June 28, 2018, the issuer entered into a share lending agreement with J.P. Morgan Securities LLC (in such capacity, the "Share Borrower") and JPMorgan Chase Bank, National Association, New York branch (as collateral agent), pursuant to which the issuer agreed to lend 7,479,431 shares (the "Borrowed Shares") of common stock of the issuer, no par value per share, to the Share Borrower. On this same date, the issuer entered into an underwriting agreement with the Share Borrower, pursuant to which the Borrowed Shares were offered and sold to the public at a price of $13.37 per share (the "Offering Price"), the closing price of the issuer's common stock on the New York Stock Exchange on June 28, 2018 (the "Offering"). In the Offering, Kapital Joe, LLC ("Kapital Joe") and R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") purchased all of the Borrowed Shares at the Offering Price. The Offering closed on July 3, 2018. Randal J. Kirk controls each of Kapital Joe, the R.J. Kirk DOT, Third Security, LLC ("Third Security"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. Randal J. Kirk controls each of Third Security Incentive 2006 LLC ("Incentive 2006"), Mascara Kaboom, LLC ("Mascara Kaboom"), Third Security Senior Staff LLC ("Sr. Staff"), ADC 2010, LLC ("ADC 2010"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2008 LLC ("Senior Staff 2008"), Third Security Staff 2010 LLC ("Staff 2010"), Third Security Incentive 2010 LLC ("Incentive 2010"), NRM VI Holdings I, LLC ("NRM VI Holdings") and NRM VII Holdings I, LLC ("NRM VII Holdings"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein. /s/ Randal J. Kirk 2018-07-06