X0202 SCHEDULE 13G/A 0001764133 XXXXXXXX LIVE 6 Common Stock 06/09/2026 0001356090 Precigen, Inc. 46122T102 20374 Seneca Meadows Parkway Germantown MD 20876 Rule 13d-1(c) Ares Trading SA V8 17467152.00 0.00 17467152.00 0.00 17467152.00 N 4.9 CO Note to Row 11: This percentage is based upon a denominator of 358,035,247 shares of Common Stock outstanding as of July 31, 2026 as reported on the cover page of the Issuer's Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2026 filed with the Securities and Exchange Commission on August 4, 2026. Merck Serono SA, Aubonne, Switzerland, an affiliate of Merck KGaA, Darmstadt V8 17467152.00 0.00 17467152.00 0.00 17467152.00 N 4.9 CO Note to Row 11: This percentage is based upon a denominator of 358,035,247 shares of Common Stock outstanding as of July 31, 2026 as reported on the cover page of the Issuer's Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2026 filed with the Securities and Exchange Commission on August 4, 2026. Merck KGaA, Darmstadt, Germany 2M 17467152.00 0.00 17467152.00 0.00 17467152.00 N 4.9 CO Note to Row 11: This percentage is based upon a denominator of 358,035,247 shares of Common Stock outstanding as of July 31, 2026 as reported on the cover page of the Issuer's Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2026 filed with the Securities and Exchange Commission on August 4, 2026. E. Merck KG, Darmstadt Germany 2M 17467152.00 0.00 17467152.00 0.00 17467152.00 N 4.9 CO Note to Row 11: This percentage is based upon a denominator of 358,035,247 shares of Common Stock outstanding as of July 31, 2026 as reported on the cover page of the Issuer's Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2026 filed with the Securities and Exchange Commission on August 4, 2026. Precigen, Inc. 20374 Seneca Meadows Parkway, Germantown, Maryland, 20876 This Schedule 13G is being filed by each of the following persons (each, a "Reporting Person" and together, the "Reporting Persons"): Ares Trading SA Merck Serono SA, Coinsins, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany Merck KGaA, Darmstadt, Germany E.Merck KG, Darmstadt, Germany The Reporting Persons have entered into a Joint Filing Agreement, a copy of which is filed with this Schedule 13G as Exhibit 99.1, pursuant to which the Reporting Persons have agreed to file this Schedule 13G jointly in accordance with the provisions of Rule 13d-1(k)(l) of the Securities Exchange Act of 1934, as amended. Ares Trading SA: Zone Industrielle de l'Outriettaz, 1170 Aubonne, Switzerland Merck Serono SA, Aubonne, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany Merck KGaA: Frankfurter Strasse 250, 64293 Darmstadt, Germany E. Merck KG: Emanuel-Merck-Platz 1, 64293 Darmstadt, Germany The Reporting Persons Ares Trading SA and Merck Serono SA Coinsins, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany are organized in Switzerland. The Reporting Persons Merck KGaA and E. Merck KG are organized in Darmstadt, Germany. Y 17,467,152 4.9% 17,467,152 0 17,467,152 0 N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Exhibit 99.1 - Joint Filing Agreement Ares Trading SA /s/ Florence Jolidon 08/07/2026 /s/ Prisca von Ballmoos 08/06/2026 Merck Serono SA, Aubonne, Switzerland, an affiliate of Merck KGaA, Darmstadt /s/ Florence Jolidon 08/07/2026 /s/ Prisca von Ballmoos 08/06/2026 Merck KGaA, Darmstadt, Germany /s/ Katharina Kneisel 08/07/2026 /s/ Abhira Gonge 08/06/2026 E. Merck KG, Darmstadt Germany /s/ Kristin Eibisch 08/06/2026 /s/ Clemens Canel 08/06/2026 Power of attorney for signatories signing as Attorney in Fact included in Exhibit 99.1 page 2