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Pay vs Performance Disclosure - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Pay vs Performance Disclosure [Table]      
Pay vs Performance [Table Text Block]
PAY VERSUS PERFORMANCE
In accordance with rules adopted by the Securities and Exchange Commission pursuant to the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010, we provide the following disclosure regarding executive compensation for our principal executive officer (“PEO”) and Non-PEO NEOs and Company performance for the fiscal years listed below. For the most recently completed fiscal year, we did not use any financial performance measure to link Compensation Actually Paid to our NEOs to the Company’s performance; accordingly, this disclosure does not present a company-selected measure in the table below nor a tabular list of our most important performance measures, as permitted by the Securities and Exchange Commission. For further information regarding our performance-based approach to executive compensation and how the Company aligns executive compensation with the Company’s performance, see “Compensation Discussion and Analysis.”
Year
Summary
Compensation
Table Total
for Helen
Sabzevari
(1)
($)
Compensation
Actually Paid
to Helen
Sabzevari
(1)(2)(3)
($)
Average
Summary
Compensation
Table Total
for Non-PEO
NEOs
(1)
($)
Average
Compensation
Actually Paid
to Non-PEO
NEOs
(1)(2)(3)
($)
Value of Initial
Fixed $100
Investment
based on:
(4)
Net Income
(Loss)
($ Millions)
(5)
TSR
($)
Peer
Group
TSR
($)
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)
2022 3,497,620 (1,088,021) 892,363 601,344 27.74 113.65 28.3
2021 2,516,168 (16,112,695) 611,020 230,396 67.70 126.45 (92.2)
2020 20,409,916 41,484,902 1,168,689 1,740,335 186.13 126.42 (170.5)
(1)
Helen Sabzevari was our PEO for each year presented. The individuals comprising the Non-PEO NEOs for each year presented are listed below.
2020
2021
2022
Donald P. Lehr
Harry Thomasian Jr.
Harry Thomasian Jr.
Jeffery Perez
Donald P. Lehr
Donald P. Lehr
Rick Sterling
Jeffery Perez
Jeffery Perez
Randal Kirk
Rick Sterling
Rutul Shah
Brad Osborne
James V. Lambert
(2)
The amounts shown for Compensation Actually Paid have been calculated in accordance with Item 402(v) of Regulation S-K and do not reflect compensation actually earned, realized, or received by the Company’s NEOs. These amounts reflect the Summary Compensation Table Total with certain adjustments as described in footnote (3) below.
(3)
Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.
Year
Summary
Compensation
Table Total
for PEO
($)
Exclusion of
Stock Awards
and Option
Awards for
PEO
($)
Inclusion
of Equity
Values for
PEO
($)
Compensation
Actually
Paid to
PEO
($)
2022
3,497,620 (2,209,127) (2,376,516) (1,088,021)
2021
2,516,168 (749,998) (17,878,865) (16,112,695)
2020
20,409,916 (18,644,600) 39,719,586 41,484,902
Year
Average
Summary
Compensation
Table Total
for Non-PEO
NEOs
($)
Average
Exclusion of
Stock Awards
and Option
Awards for
Non-PEO
NEOs
($)
Average
Inclusion of
Equity Values
for Non-PEO
NEOs
($)
Average
Compensation
Actually
Paid to
Non-PEO
NEOs
($)
2022
892,363 (357,307) 66,288 601,344
2021
611,020 (215,235) (165,389) 230,396
2020
1,168,689 (653,440) 1,225,086 1,740,335
The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables. The Company does not pay any dividends and consequently, no adjustment for dividends is shown in the following tables.
Year
Year-End
Fair Value
of Equity
Awards
Granted
During
Year That
Remained
Unvested
as of Last
Day of Year
for PEO
($)
Change in
Fair Value
from Last
Day of Prior
Year to Last
Day of Year
of Unvested
Equity Awards
for PEO
($)
Vesting-Date
Fair Value
of Equity
Awards
Granted
During
Year that
Vested During
Year for PEO
($)
Change in
Fair Value
from Last
Day of Prior
Year to
Vesting
Date of
Unvested
Equity Awards
that Vested
During Year
for PEO
($)
Fair Value
at Last Day
of Prior Year
of Equity
Awards
Forfeited
During Year
for PEO
($)
Total – 
Inclusion of
Equity
Values
for PEO
($)
2022
933,566 (3,366,326) 426,136 (369,892) 0 (2,376,516)
2021
0 (17,338,751) 662,450 (1,202,564) 0 (17,878,865)
2020
37,870,674 595,965 1,300,000 (47,053) 0 39,719,586
Year
Average
Year-End
Fair Value
of Equity
Awards
Granted
During
Year That
Remained
Unvested as of
Last Day of
Year for
Non-PEO
NEOs
($)
Average
Change in
Fair Value
from Last
Day of Prior
Year to
Last Day of
Year of
Unvested
Equity
Awards for
Non-PEO
NEOs
($)
Average
Vesting-Date
Fair Value
of Equity
Awards
Granted
During
Year that
Vested During
Year for
Non-PEO
NEOs
($)
Average
Change in
Fair Value
from Last
Day of Prior
Year to
Vesting Date
of Unvested
Equity Awards
that Vested
During Year
for Non-PEO
NEOs
($)
Average
Fair Value
at Last Day
of Prior Year
of Equity
Awards
Forfeited
During Year
for Non-PEO
NEOs
($)
Total – 
Average
Inclusion
of Equity
Values for
Non-PEO
NEOs
($)
2022
192,885 (122,266) 32,298 (36,629) 0 66,288
2021
84,641 (105,418) 65,018 (47,094) (162,536) (165,389)
2020
136,606 429,872 692,095 (33,487) 0 1,225,086
For the values of equity awards included in the above tables, the valuation of certain stock option awards uses the Black-Scholes option-pricing model with volatility assumptions that may differ materially from those disclosed as of the grant date. For purposes of this table, full reliance on the Company’s historical volatility was used even in cases where there was not full history, when on the grant date, a weighted blend of the Company’s volatility and the average historical peer volatilities was used.
(4)
The Peer Group TSR set forth in this table utilizes the NASDAQ Biotechnology Index, which we also utilize in the stock performance graph required by Item 201(e) of Regulation S-K included in our Annual Report for the year ended December 31, 2022. The comparison assumes $100 was invested for the period starting December 31, 2019, through the end of each of the listed years in the Company and in the NASDAQ Biotechnology Index, respectively. Historical stock performance is not necessarily indicative of future stock performance.
(5)
Reflects “Net Income (loss)” for each applicable year as set forth in our Consolidated Statements of Operations included in our Annual Report on Form 10-K for each of the applicable years.
   
Named Executive Officers, Footnote [Text Block]
(1)
Helen Sabzevari was our PEO for each year presented. The individuals comprising the Non-PEO NEOs for each year presented are listed below.
2020
2021
2022
Donald P. Lehr
Harry Thomasian Jr.
Harry Thomasian Jr.
Jeffery Perez
Donald P. Lehr
Donald P. Lehr
Rick Sterling
Jeffery Perez
Jeffery Perez
Randal Kirk
Rick Sterling
Rutul Shah
Brad Osborne
James V. Lambert
   
Changed Peer Group, Footnote [Text Block]
(4)
The Peer Group TSR set forth in this table utilizes the NASDAQ Biotechnology Index, which we also utilize in the stock performance graph required by Item 201(e) of Regulation S-K included in our Annual Report for the year ended December 31, 2022. The comparison assumes $100 was invested for the period starting December 31, 2019, through the end of each of the listed years in the Company and in the NASDAQ Biotechnology Index, respectively. Historical stock performance is not necessarily indicative of future stock performance
   
PEO Total Compensation Amount $ 3,497,620 $ 2,516,168 $ 20,409,916
PEO Actually Paid Compensation Amount $ (1,088,021) (16,112,695) 41,484,902
Adjustment To PEO Compensation, Footnote [Text Block]
(3)
Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.
Year
Summary
Compensation
Table Total
for PEO
($)
Exclusion of
Stock Awards
and Option
Awards for
PEO
($)
Inclusion
of Equity
Values for
PEO
($)
Compensation
Actually
Paid to
PEO
($)
2022
3,497,620 (2,209,127) (2,376,516) (1,088,021)
2021
2,516,168 (749,998) (17,878,865) (16,112,695)
2020
20,409,916 (18,644,600) 39,719,586 41,484,902
The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables. The Company does not pay any dividends and consequently, no adjustment for dividends is shown in the following tables.
Year
Year-End
Fair Value
of Equity
Awards
Granted
During
Year That
Remained
Unvested
as of Last
Day of Year
for PEO
($)
Change in
Fair Value
from Last
Day of Prior
Year to Last
Day of Year
of Unvested
Equity Awards
for PEO
($)
Vesting-Date
Fair Value
of Equity
Awards
Granted
During
Year that
Vested During
Year for PEO
($)
Change in
Fair Value
from Last
Day of Prior
Year to
Vesting
Date of
Unvested
Equity Awards
that Vested
During Year
for PEO
($)
Fair Value
at Last Day
of Prior Year
of Equity
Awards
Forfeited
During Year
for PEO
($)
Total – 
Inclusion of
Equity
Values
for PEO
($)
2022
933,566 (3,366,326) 426,136 (369,892) 0 (2,376,516)
2021
0 (17,338,751) 662,450 (1,202,564) 0 (17,878,865)
2020
37,870,674 595,965 1,300,000 (47,053) 0 39,719,586
   
Non-PEO NEO Average Total Compensation Amount $ 892,363 611,020 1,168,689
Non-PEO NEO Average Compensation Actually Paid Amount $ 601,344 230,396 1,740,335
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
(3)
Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.
Year
Average
Summary
Compensation
Table Total
for Non-PEO
NEOs
($)
Average
Exclusion of
Stock Awards
and Option
Awards for
Non-PEO
NEOs
($)
Average
Inclusion of
Equity Values
for Non-PEO
NEOs
($)
Average
Compensation
Actually
Paid to
Non-PEO
NEOs
($)
2022
892,363 (357,307) 66,288 601,344
2021
611,020 (215,235) (165,389) 230,396
2020
1,168,689 (653,440) 1,225,086 1,740,335
The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables. The Company does not pay any dividends and consequently, no adjustment for dividends is shown in the following tables.
Year
Average
Year-End
Fair Value
of Equity
Awards
Granted
During
Year That
Remained
Unvested as of
Last Day of
Year for
Non-PEO
NEOs
($)
Average
Change in
Fair Value
from Last
Day of Prior
Year to
Last Day of
Year of
Unvested
Equity
Awards for
Non-PEO
NEOs
($)
Average
Vesting-Date
Fair Value
of Equity
Awards
Granted
During
Year that
Vested During
Year for
Non-PEO
NEOs
($)
Average
Change in
Fair Value
from Last
Day of Prior
Year to
Vesting Date
of Unvested
Equity Awards
that Vested
During Year
for Non-PEO
NEOs
($)
Average
Fair Value
at Last Day
of Prior Year
of Equity
Awards
Forfeited
During Year
for Non-PEO
NEOs
($)
Total – 
Average
Inclusion
of Equity
Values for
Non-PEO
NEOs
($)
2022
192,885 (122,266) 32,298 (36,629) 0 66,288
2021
84,641 (105,418) 65,018 (47,094) (162,536) (165,389)
2020
136,606 429,872 692,095 (33,487) 0 1,225,086
   
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Description of Relationship Between PEO and Non-PEO NEO Compensation Actually Paid and Company Total Shareholder Return (“TSR”)
The following chart sets forth the relationship between Compensation Actually Paid to our PEO, the average of Compensation Actually Paid to our Non-PEO NEOs, and the Company’s cumulative TSR over the three most recently completed fiscal years.
[MISSING IMAGE: bc_tsr-4clr.jpg]
   
Compensation Actually Paid vs. Net Income [Text Block]
Description of Relationship Between PEO and Non-PEO NEO Compensation Actually Paid and Net Income (loss)
The following chart sets forth the relationship between Compensation Actually Paid to our PEO, the average of Compensation Actually Paid to our Non-PEO NEOs, and our Net Income (loss) during the three most recently completed fiscal years.
[MISSING IMAGE: bc_netincome-4clr.jpg]
   
Total Shareholder Return Amount $ 27.74 67.7 186.13
Peer Group Total Shareholder Return Amount 113.65 126.45 126.42
Net Income (Loss) $ 28,300,000 (92,200,000) (170,500,000)
PEO Name Helen Sabzevari    
Additional 402(v) Disclosure [Text Block]
[MISSING IMAGE: bc_nasdaq-4clr.jpg]
   
PEO [Member] | Exclusion of Stock Awards and Option Awards      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount $ (2,209,127) (749,998) (18,644,600)
PEO [Member] | Inclusion of Equity Values      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (2,376,516) (17,878,865) 39,719,586
PEO [Member] | Year-End Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 933,566 0 37,870,674
PEO [Member] | Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (3,366,326) (17,338,751) 595,965
PEO [Member] | Vesting-Date Fair Value of Equity Awards Granted During Year that Vested During Year      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 426,136 662,450 1,300,000
PEO [Member] | Change in Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (369,892) (1,202,564) (47,053)
PEO [Member] | Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0 0 0
Non-PEO NEO [Member] | Exclusion of Stock Awards and Option Awards      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (357,307) (215,235) (653,440)
Non-PEO NEO [Member] | Inclusion of Equity Values      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 66,288 (165,389) 1,225,086
Non-PEO NEO [Member] | Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (122,266) (105,418) 429,872
Non-PEO NEO [Member] | Change in Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (36,629) (47,094) (33,487)
Non-PEO NEO [Member] | Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0 (162,536) 0
Non-PEO NEO [Member] | Non-PEO NEO [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 192,885 84,641 136,606
Non-PEO NEO [Member] | Change In Fair Value As Of Vesting Date Of Current Year Awards Vested During Current Year [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount $ 32,298 $ 65,018 $ 692,095