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Consolidated Statements of Comprehensive Loss (unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Statement Of Income And Comprehensive Income [Abstract]    
Net loss $ (11,868) $ (11,601)
Other comprehensive gain (loss):    
Net change in unrealized gains (losses) on marketable securities 1 (2)
Comprehensive loss $ (11,867) $ (11,603)