<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>5</documentType>

    <periodOfReport>2009-12-31</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <form3HoldingsReported>1</form3HoldingsReported>

    <form4TransactionsReported>0</form4TransactionsReported>

    <issuer>
        <issuerCik>0000810084</issuerCik>
        <issuerName>BIOJECT MEDICAL TECHNOLOGIES INC</issuerName>
        <issuerTradingSymbol>BJCT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001355566</rptOwnerCik>
            <rptOwnerName>Cobbs Jerald S</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>20245 SW 95TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>TUALATIN</rptOwnerCity>
            <rptOwnerState>OR</rptOwnerState>
            <rptOwnerZipCode>97062</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Series D Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.41</value>
            </conversionOrExercisePrice>
            <transactionCoding>
                <transactionFormType>3</transactionFormType>
            </transactionCoding>
            <exerciseDate>
                <value>2004-12-15</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>BJCT Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2086957</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2086957</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>LOF Funds II &amp; LOF Funds II Institutional</value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series E Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.37</value>
            </conversionOrExercisePrice>
            <transactionCoding>
                <transactionFormType>3</transactionFormType>
            </transactionCoding>
            <exerciseDate>
                <value>2006-03-08</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>BJCT Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1838102</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1838102</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>LOF Funds II &amp; LOF Funds II Institutional</value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series FF Warrant</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.37</value>
            </conversionOrExercisePrice>
            <transactionCoding>
                <transactionFormType>3</transactionFormType>
            </transactionCoding>
            <exerciseDate>
                <value>2006-03-08</value>
            </exerciseDate>
            <expirationDate>
                <value>2010-09-07</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>BJCT Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>364965</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>364965</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>LOF Funds II &amp; LOF Funds II Institutional</value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series IIB Warrant</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.75</value>
            </conversionOrExercisePrice>
            <transactionCoding>
                <transactionFormType>3</transactionFormType>
            </transactionCoding>
            <exerciseDate>
                <value>2007-12-04</value>
            </exerciseDate>
            <expirationDate>
                <value>2011-12-04</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>BJCT Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>80000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>80000</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>LOF Funds II &amp; LOF Funds II Institutional</value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series G Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.13</value>
            </conversionOrExercisePrice>
            <transactionCoding>
                <transactionFormType>3</transactionFormType>
            </transactionCoding>
            <exerciseDate>
                <value>2009-12-18</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>BJCT Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>8860262</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8860262</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>LOF Funds II &amp; LOF Funds II Institutional</value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">No expiration date.</footnote>
        <footnote id="F2">The reporting person is a general partner of Signet Healthcare Partners, which owns the partnership of the reported securities,  who disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial owners of all of the reported shares for purposes of Section 16 or for any other purpose.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>//Christine M. Farrell Attorney-in-Fact for Jerald S Cobbs//</signatureName>
        <signatureDate>2010-02-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
