NPORT-P false 0001355064 XXXXXXXX S000039514 C000121709 C000121707 C000121710 C000121708 MUTUAL FUND SERIES TRUST 811-21872 0001355064 5493002ZGLQMLR4QMA96 C/O GEMINI FUND SERVICES LLC 4221 North 203rd Street, Suite 100 ELKHORN 68022 631-470-2600 Eventide Healthcare & Life Sciences Fund S000039514 549300Q3GKE6GIU0KZ79 2021-06-30 2020-09-30 N 1714229077.93 4096869.98 1710132207.95 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 N Oak Street Health Inc N/A 67181A107 5000.00000000 NS USD 267200.00000000 0.015624522990 Long EC CORP US N 1 N N N Repligen Corporation 54930006QJ0T5AUO1E71 759916109 119000.00000000 NS USD 17557260.00000000 1.026660975004 Long EC CORP US N 1 N N N BETA BIONIC SERIES B N/A N/A 122828.00000000 NS USD 18669856.00000000 1.091720038556 Long EP US Y 3 N N N Collegium Pharmaceutical Inc 54930049FXZMTLW8D496 19459J104 1083600.00000000 NS USD 22560552.00000000 1.319228530701 Long EC CORP US N 1 N N N Crinetics Pharmaceuticals Inc 549300Q1CNFXK5P31D28 22663K107 1347000.00000000 NS USD 21107490.00000000 1.234260713989 Long EC CORP US N 1 N N N Kura Oncology Incorporation 5493005QORQTZCZYOP39 50127T109 400000.00000000 NS USD 12256000.00000000 0.716669737171 Long EC CORP US N 1 N N N Xenon Pharmaceuticals Inc 549300XV44Q9Z1MIPQ03 98420N105 1274100.00000000 NS USD 14104287.00000000 0.824748340182 Long EC CORP CA N 1 N N N ROCKET PHARMACEUTICALS INC 549300R7VV82YUIN4Y93 77313F106 1550000.00000000 NS USD 35433000.00000000 2.071945071572 Long EC CORP US N 1 N N N Myokardia Incorporation 549300OLNNNZ1NI9UY54 62857M105 621000.00000000 NS USD 84660930.00000000 4.950548829291 Long EC CORP US N 1 N N N Relay Therapeutics Inc N/A 75943R102 250000.00000000 NS USD 10647500.00000000 0.622612681668 Long EC CORP US N 1 N N N Karuna Therapeutics Inc N/A 48576A100 901077.00000000 NS USD 69671273.64000000 4.074028505873 Long EC CORP US N 1 N N N Pliant Therapeutics Inc 5493002Q5LITR7VHZH02 729139105 550000.00000000 NS USD 12457500.00000000 0.728452451926 Long EC CORP US N 1 N N N Kalvista Pharmaceuticals Inc 529900Q7IDA3WUGRZA51 483497103 1680000.00000000 NS USD 21151200.00000000 1.236816656728 Long EC CORP US N 1 N N N 89Bio Incorporation N/A 282559103 675000.00000000 NS USD 17320500.00000000 1.012816431354 Long EC CORP US N 1 N N N Fidelity Institutional Cash 549300SHPEJB1OPRCV46 316175108 3116796.06000000 PA USD 3116796.06000000 0.182254684492 Long STIV RF IE N 1 N N N Eidos Therapeutics Inc 549300VGYGU07QRG6271 28249H104 317417.00000000 NS USD 16039081.01000000 0.937885441572 Long EC CORP US N 1 N N N Immatics N.V 984500DC691EZ96AF394 N44445109 800000.00000000 NS USD 8488000.00000000 0.496335894999 Long EC CORP NL N 1 N N N N/A N/A N/A 8474576.00000000 NS USD 9491525.12000000 0.555017037622 Long EP US Y 3 N N N Chemocentryx Inc 529900YTTXUSFQTAKY40 16383L106 297000.00000000 NS USD 16275600.00000000 0.951715892159 Long EC CORP US N 1 N N N Adc Therapeutics Sa N/A H0036K147 580483.00000000 NS USD 19150134.17000000 1.119804309922 Long EC CORP CH N 1 N N N Trillium Therapeutics Inc N/A 89620X506 3197008.00000000 NS USD 45429483.68000000 2.656489566643 Long EC CORP CA N 1 N N N PRAXIS PRECISION MEDICINES, INC N/A N/A 1941748.00000000 NS USD 10459225.60000000 0.611603334021 Long EC US Y 3 N N N Sarepta Therapeutics Inc 549300IKDPIED8J8IG21 803607100 515000.00000000 NS USD 72321450.00000000 4.228997598185 Long EC CORP US N 1 N N N Veracyte Inc 529900ESWZRHXOW27Z37 92337F107 930000.00000000 NS USD 30215700.00000000 1.766863395679 Long EC CORP US N 1 N N N N/A N/A N/A 5000000.00000000 NS USD 3562500.00000000 0.208317227372 Long EC US Y 3 N N N PRAXIS PRECISION MEDICINES, INC N/A N/A 2116402.00000000 NS USD 11399999.37000000 0.666615090751 Long EC US Y 3 N N N Zentalis Pharmaceuticals Inc N/A 98943L107 316711.00000000 NS USD 10353282.59000000 0.605408315326 Long EC CORP US N 2 N N N PLIANT THERAPEUTICS SRS B N/A N/A 229279.00000000 NS USD 4933510.88000000 0.288487103924 Long EP US Y 2 N N N Outset Medical Inc N/A 690145107 13636.00000000 NS USD 681800.00000000 0.039868262630 Long EC CORP US N 1 N N N Acceleron Pharma Inc 529900TQRID2UY164805 00434H108 142900.00000000 NS USD 16080537.00000000 0.940309581051 Long EC CORP US N 1 N N N Fennec Pharmaceuticals Inc 5299003IE70ITO2CBM73 31447P100 1120000.00000000 NS USD 6787200.00000000 0.396881595963 Long EC CORP CA N 1 N N N N/A N/A N/A 6082133.00000000 NS USD 6650204.22000000 0.388870766194 Long EP CH Y 3 N N N GoodRx Holdings Inc N/A 38246G108 2000.00000000 NS USD 111200.00000000 0.006502421244 Long EC CORP US N 1 N N N Allakos Inc 549300S6ZD1W6BPMDY37 01671P100 160000.00000000 NS USD 13032000.00000000 0.762046345856 Long EC CORP US N 1 N N N Global Blood Therapeutics Incorporation 549300U4G0QKK99GRT15 37890U108 535000.00000000 NS USD 29499900.00000000 1.725006982668 Long EC CORP US N 1 N N N Xencor Inc 549300V5IF65437JKG30 98401F105 300000.00000000 NS USD 11637000.00000000 0.680473705243 Long EC CORP US N 1 N N N Nurix Therapeutics Inc N/A 67080M103 497740.00000000 NS USD 17376103.40000000 1.016067840791 Long EC CORP US N 1 N N N Galapagos Nv 549300QKJ78IY0IOV655 36315X101 51000.00000000 NS USD 7237410.00000000 0.423207630752 Long EC CORP BE N 1 N N N US BANK MMDA N/A N/A 35000000.00000000 PA USD 35000000.00000000 2.046625391726 Long STIV US N 1 N N N Ascendis Pharma A/S 549300B66JN3W3J8GH73 04351P101 575648.00000000 NS USD 88833999.36000000 5.194569106822 Long EC CORP DK N 1 N N N Freeline Therapeutics Holdings plc 21380046L1D1Q6QJPH29 35655L107 1115000.00000000 NS USD 17405150.00000000 1.017766341051 Long EC CORP GB N 1 N N N Blueprint Medicines Corporation 5299004CC60O9T5HVM83 09627Y109 462000.00000000 NS USD 42827400.00000000 2.504332694332 Long EC CORP US N 1 N N N American Well Corporation N/A 03044L105 110091.00000000 NS USD 3263097.24000000 0.190809647630 Long EC CORP US N 1 N N N N/A N/A N/A 798111.00000000 NS USD 22920550.75000000 1.340279461637 Long EP US Y 2 N N N Chiasma Incorporation 549300PP2WZZEZZ6XS69 16706W102 3000326.00000000 NS USD 12901401.80000000 0.754409614649 Long EC CORP US N 1 N N N Entasis Therapeutics Hldgs Inc N/A 293614103 288939.00000000 NS USD 559963.78000000 0.032743888302 Long EC CORP US Y 1 N N N N/A N/A N/A 3804347.00000000 NS USD 6649998.56000000 0.388858740224 Long EC US Y 3 N N N Immunovant Inc N/A 45258J102 932000.00000000 NS USD 32797080.00000000 1.917809620071 Long EC CORP US N 1 N N N Seattle Genetics I N/A 812578102 102500.00000000 NS USD 20058225.00000000 1.172904931370 Long EC CORP US N 1 N N N GW Pharmaceuticals 213800ISBN5CNUZMHZ39 36197T103 230000.00000000 NS USD 22390500.00000000 1.309284738098 Long EC CORP GB N 1 N N N PLIANT THERAPEUTICS SRS B N/A N/A 507954.00000000 NS USD 10929900.20000000 0.639126036524 Long EP US Y 2 N N N Annexon Inc N/A 03589W102 975000.00000000 NS USD 29474250.00000000 1.723507098631 Long EC CORP US N 1 N N N FIRST AMERN FDS INC N/A 31846V211 138695104.99000000 PA USD 138695104.99000000 8.110197816592 Long STIV RF US N 1 N N N Essa Pharma Incorporation N/A 29668H708 1716522.30000000 NS USD 11251803.68000000 0.657949346120 Long EC CORP CA N 1 N N N Sutro Biopharma Inc 5493005U6P15VD25P851 869367102 1985975.00000000 NS USD 19959048.75000000 1.167105599041 Long EC CORP US N 1 N N N N/A N/A N/A 5000000.00000000 NS USD 5600000.00000000 0.327460062676 Long EP US Y 3 N N N Magenta Therapeutics Inc 549300Z3N6ODPCOFC890 55910K108 2359646.00000000 NS USD 16045592.80000000 0.938266218565 Long EC CORP US N 1 N N N Turning Point Therapeutics Inc N/A 90041T108 383000.00000000 NS USD 33458880.00000000 1.956508382478 Long EC CORP US N 1 N N N EXACT SCIENCES CORPORATION 549300VM3X1FYD4N9Z14 30063P105 703000.00000000 NS USD 71670850.00000000 4.190953755903 Long EC CORP US N 1 N N N Celldex Therapeuti 529900F018DMYWH38923 15117B202 506179.00000000 NS USD 7506634.57000000 0.438950540496 Long EC CORP US N 1 N N N Argenx SE 7245009C5FZE6G9ODQ71 04016X101 160000.00000000 NS USD 42003200.00000000 2.456137590107 Long EC CORP NL N 1 N N N Arvinas Inc N/A 04335A105 230000.00000000 NS USD 5430300.00000000 0.317536853276 Long EC CORP US N 1 N N N N/A N/A N/A 1528871.00000000 NS USD 1314523.29000000 0.076866764095 Long EC US Y 3 N N N Immatics N.V 984500DC691EZ96AF394 N44445117 400000.00000000 NS USD 1380000.00000000 0.080695515445 Long DO CORP NL N 2 US BANK N/A Call Purchased Immatics NV warrants 400000.00000000 11.50000000 USD 2025-12-31 XXXX 306952.00000000 N N N Syndax Pharmaceuticals Inc 529900OF94TRHKZVBS87 87164F105 699200.00000000 NS USD 10320192.00000000 0.603473342705 Long EC CORP US N 1 N N N Neurocrine Biosciences Inc 549300FECER0XBN49756 64125C109 353000.00000000 NS USD 33944480.00000000 1.984903847913 Long EC CORP US N 1 N N N Avrobio Inc. N/A 05455M100 1305307.00000000 NS USD 16995097.14000000 0.993788495473 Long EC CORP US N 1 N N N Deciphera Pharmaceuticals Inc 529900QR4WAPYY0CBF25 24344T101 243000.00000000 NS USD 12465900.00000000 0.728943642020 Long EC CORP US N 1 N N N Biohaven Pharmaceutical Holding Company Limited 5299007STZTNN32O9920 G11196105 1181761.00000000 NS USD 76826282.61000000 4.492417735474 Long EC CORP VG N 1 N N N Regeneron Pharmaceuticals, Inc. 549300RCBFWIRX3HYQ56 75886F107 30900.00000000 NS USD 17297202.00000000 1.011454080543 Long EC CORP US N 1 N N N Mirati Therapeutics Inc 529900GYRW59IDQV6N54 60468T105 301000.00000000 NS USD 49981050.00000000 2.922642458147 Long EC CORP US N 1 N N N N/A N/A N/A 1228304.00000000 NS USD 18215134.17000000 1.065130174457 Long EP GB Y 3 N N N Kala Pharmaceuticals Inc 529900Y7RO0C9P0TX474 483119103 3450000.00000000 NS USD 25875000.00000000 1.513040914597 Long EC CORP US N 1 N N N N/A N/A N/A 594705.00000000 NS USD 18468861.13000000 1.079966861283 Long EP US Y 2 N N N 2020-10-28 MUTUAL FUND SERIES TRUST Erik Naviloff Erik Naviloff Treasurer XXXX