X0306 4 2020-02-14 0 0001367920 CONCERT PHARMACEUTICALS, INC. CNCE 0001353528 Cassella James V C/O CONCERT PHARMACEUTICALS, INC. 65 HAYDEN AVENUE, SUITE 3000N LEXINGTON MA 02421 0 1 0 0 Chief Development Officer Common Stock 2020-02-14 4 A 0 28216 A 80481 D Stock Option (Right to Buy) 10.87 2020-02-14 4 A 0 42430 0.00 A 2030-02-13 Common Stock 42430 42430 D Each restricted stock unit ("RSU") represents a contingent right to receive one share of Common Stock of the Issuer. The RSUs granted to Mr. Cassella will vest in three equal annual installments measured from the date of grant. The number above represents the maximum number of shares that may be delivered pursuant to the award. Not applicable. The shares underlying this option vest in equal quarterly installments over a four-year period measured from the date of grant. /s/ Nancy Stuart as Attorney-in-Fact for James V. Cassella 2020-02-19