X0303 4 2010-11-12 0000005768 AMERICAN SCIENCE & ENGINEERING, INC. ASEI 0001353373 Breur Kenneth AMERICAN SCIENCE AND ENGINEERING, INC. 829 MIDDLESEX TURNPIKE BILLERICA MA 01821 0 1 0 0 SVP Common Stock 2010-11-12 4 M 0 560 52.82 A 10766 D Common Stock 2010-11-12 4 M 0 935 61.45 A 11701 D Common Stock 2010-11-12 4 M 0 151 60.66 A 11852 D Common Stock 2010-11-12 4 M 0 469 51.56 A 12321 D Common Stock 2010-11-12 4 S 0 2115 82.52 D 10206 D Common Stock 2010-11-15 4 S 0 2800 83.00 D 7406 D Stock Options (Right to buy) 52.82 2010-11-12 4 M 0 560 0 D 2016-06-20 Common Stock 560 0 D Stock Options (Right to buy) 61.45 2010-11-12 4 M 0 935 0 D 2017-08-15 Common Stock 935 0 D Stock Options (Right to buy) 60.66 2010-11-12 4 M 0 151 0 D 2017-09-14 Common Stock 151 0 D Stock Options (Right to buy) 51.56 2010-11-12 4 M 0 469 0 D 2018-06-12 Common Stock 469 235 D The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from a low of $82.50 to a high of $82.58 for an average of $82.5213. The reporting person undertakes to provide to American Science and Engineering, Inc., any security holder of American Science and Engineering, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. On June 20, 2006, the reporting person was granted an option to purchase 560 shares of common stock. The option vests in 3 equal increments based on AS&E's satisfaction of certain performance criteria for each of the fiscal years ending March 31, 2007, 2008, and 2009. The performance criteria were met, resulting in vesting of the option as to 560 shares. On August 15, 2007, the reporting person was granted an option to purchase 935 shares of common stock. The option vests in 3 equal increments based on AS&E's satisfaction of certain performance criteria for each of the fiscal years ending March 31, 2008, 2009 and 2010. The performance criteria were met, resulting in vesting of the option as to 935 shares. On September 14, 2007, the reporting person was granted an option to purchase 151 shares of common stock. The option vests in 3 equal increments based on AS&E's satisfaction of certain performance criteria for each of the fiscal years ending March 31, 2008, 2009 and 2010. The performance criteria were met, resulting in vesting of the option as to 151shares. On June 12, 2008, the reporting person was granted an option to purchase 704 shares of common stock. The option vests in 3 equal increments based on AS&E's satisfaction of certain performance criteria for each of the fiscal years ending March 31, 2009, 2010 and 2011. The performance criteria were met for 2009 and 2010, resulting in vesting of the option as to 469 shares. M. Colette Cooke 2010-11-16