X0306 4 2013-02-14 0000005768 AMERICAN SCIENCE & ENGINEERING, INC. ASEI 0001352965 Grazewski Paul AMERICAN SCIENCE AND ENGINEERING, INC. 829 MIDDLESEX TURNPIKE BILLERICA MA 01821 0 1 0 0 SVP Common Stock 2013-02-14 4 S 0 1400 64.55 D 6295 D Common Stock 2013-02-14 4 M 0 3000 39.06 A 9295 D Common Stock 2013-02-14 4 S 0 3000 63.99 D 6295 D Common Stock 2078 I By 401(k) Plan Employee Stock Option (Right to Buy) 39.06 2013-02-14 4 M 0 3000 0 D 2007-12-02 2014-12-02 Common Stock 3000 0 D The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from a low of $64.47 to a high of $64.74 for an average of $64.5526. The reporting person undertakes to provide to American Science and Engineering, Inc., any security holder of American Science and Engineering, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from a low of $63.5018 to a high of $64.49 for an average of $63.992. The reporting person undertakes to provide to American Science and Engineering, Inc., any security holder of American Science and Engineering, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. Includes 2,078 shares of AS&E common stock acquired under the AS&E 401(k) Plan. The information in this report is based on a plan statement dated as of February 15, 2013. /s/John B. De Luca, attorney-in-fact 2013-02-19