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Summary of Significant Accounting Policies - Anti-Dilutive Securities of Common Stock Excluded from Calculation of Diluted Net Loss Per Share (Details) - shares
shares in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities not included in diluted net loss per share (in shares) 49,578 37,077
Series A Convertible Preferred Stock    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities not included in diluted net loss per share (in shares) 29 29
Options to purchase common stock and employee stock purchase plan    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities not included in diluted net loss per share (in shares) 3,416 3,951
Unvested restricted stock units    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities not included in diluted net loss per share (in shares) 8,703 8,216
Warrants to purchase common stock    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities not included in diluted net loss per share (in shares) 20,184 24,881
Senior Convertible Notes    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities not included in diluted net loss per share (in shares) 17,246