Income Taxes - Additional Information (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Income Tax [Line Items]
Tax expense in discontinued operations	$ 6,500
Deferred tax asset, valuation allowance	$ (58,202)	$ (63,612)
Number of years cumulative pre-tax loss	3 years
Unrecognized tax benefits	$ 9,331	$ 10,359	$ 8,861	$ 7,835
Uncertain tax benefits that, if realized, would affect the effective tax rate	7,900
Reduction in unrecognized tax benefit within the next 12 months	600
Accrued interest and penalties	1,100
Decrease in accrued interest and penalties	100
Operating loss carryforwards state	91,900
Operating loss carryforwards federal	$ 113,900
Federal and state net operating loss carryforwards, expiring year	2036
Federal research and development tax credits	$ 3,400
State research and development tax credits	3,100
Operating loss carryforwards foreign	$ 14,900
Federal research and development tax credits [Member]
Income Tax [Line Items]
Federal research and development tax credits expiration year	2036
Earliest Tax Year | Scient'x [Member]
Income Tax [Line Items]
Tax year	2013
Latest Tax Year | Scient'x [Member]
Income Tax [Line Items]
Tax year	2014