Debt - Long-Term Debt (Detail) - USD ($)	Dec. 31, 2016	Sep. 01, 2016	Dec. 31, 2015	Nov. 21, 2014	Mar. 20, 2014	Mar. 17, 2014
Debt Instrument [Line Items]
Notes payable	$ 1,395,000		$ 1,788,000
Total	49,268,000		84,587,000
Add: capital leases	480,000		1,277,000
Less: debt discount	(3,543,000)		(5,642,000)
Total	46,205,000		80,222,000
Less: current portion of long-term debt	(3,113,000)		(79,742,000)
Total long-term debt, net of current portion	43,092,000		480,000
Globus facility agreement
Debt Instrument [Line Items]
Maximum borrowing capacity	30,000,000	$ 30,000,000
Less: debt discount	(1,000,000)
Amended credit facility with MidCap
Debt Instrument [Line Items]
Maximum borrowing capacity	17,873,000		56,799,000
Less: debt discount	$ (1,900,000)
Deerfield
Debt Instrument [Line Items]
Maximum borrowing capacity			$ 26,000,000			$ 50,000,000
Less: debt discount				$ (200,000)	$ (500,000)